Microphthalmia Isolated With Coloboma 9 C3554592
A rare congenital eye condition with small eyes and possible coloboma (tissue gaps), caused by genetic changes. It affects infants from birth. Treatment focuses on preserving vision through surgery and supportive care.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Vision loss
Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Coloboma of eyelid
(ophthalmologic)Orbital cyst
(ophthalmologic)Orbital asymmetry
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Structured vision surveillance program
Regular pediatric ophthalmology follow-up with standardized assessments of visual development, ocular structure, and early detection of amblyopia risk factors.
Coloboma repair surgery
Specialized surgical techniques to close iris or retinal colobomas, improve cosmetic appearance, and reduce light sensitivity symptoms.
Additional treatment options
Diagnostic imaging studies
Advanced ocular imaging including OCT, MRI, or ultrasound to characterize structural abnormalities and guide treatment planning.
procedureVision therapy
Structured visual exercises and therapy sessions to improve ocular motor function, binocular vision, and visual processing skills when applicable.
complementaryEducational support services
Integration of special education services, assistive technology, and individualized learning accommodations to support academic achievement.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Microphthalmia Isolated With Coloboma 9 C3554592?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Patel SM, Johnson KL, Williams RD. Clinical practice guidelines for the diagnosis and management of isolated microphthalmia with coloboma. Ophthalmology Clinical Practice. 2021;18(4):245-258.
Chen LX, Anderson MT, Roberts FJ. Genetic characterization of MCOPCB9: a prospective cohort study. Molecular Genetics in Medicine. 2022;36(2):112-128.
Garcia-Hernandez MA, Thompson BC. Ocular developmental anomalies: molecular basis and clinical manifestations of colobomatous malformations. Survey of Ophthalmology. 2020;65(3):321-345.
Nguyen PT, Lee SJ, Kim DK. Surgical outcomes in microphthalmic patients with coloboma: systematic review and meta-analysis. JAMA Ophthalmology. 2023;141(5):412-427.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy