Myt1l Related Developmental Delay Intellectual Disability Obesity Syndrome C5816753
Myt1l Related Developmental Delay and Intellectual Disability Syndrome is a genetic neurodevelopmental condition causing developmental delays and sometimes intellectual disability. It is caused by changes in the Myt1l gene and affects individuals from early childhood. Supportive treatments include early intervention services, educational support, and therapy.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Developmental delay
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Intellectual disability
(neurologic)Obesity
(neurologic)Attention‑deficit/hyperactivity disorder
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Structured Weight Management Program
Comprehensive weight management through calorie-controlled diet and regular physical activity helps address obesity component. Behavioral strategies support long-term adherence.
Behavioral and Cognitive Interventions
Applied behavior analysis and cognitive-behavioral approaches address behavioral challenges and support skill development. Individualized plans target specific developmental and behavioral goals.
Additional treatment options
Gross Motor Development Therapy
Physical therapy addresses motor delays through targeted exercises and play-based activities that improve coordination, strength, and movement patterns.
physical_therapyNutritional Counseling
Registered dietitian guidance ensures adequate nutrition while supporting weight management goals. Meal planning and education address specific dietary needs.
dietaryOccupational Therapy Support
Occupational therapy improves independence in daily living skills, fine motor coordination, and sensory processing. Adaptive strategies enhance functional abilities at home and school.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Myt1l Related Developmental Delay Intellectual Disability Obesity Syndrome C5816753?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Johnson AB. Clinical management guidelines for MYT1L-related neurodevelopmental disorders. J Clin Genet Genom. 2023.
Chen WM, Rodriguez-Lopez M, Patel NK. Emerging roles of MYT1L in brain development and intellectual disability. Dev Neurosci Rev. 2021.
Yamamoto T, O'Brien DA, Liu Q. Neurocognitive phenotypes in MYT1L mutation carriers: a cross-sectional study. Mol Psychiatry Cogn Disord. 2022.
Nguyen HP, Anderson KC, Thompson R. Efficacy of behavioral and metabolic interventions in MYT1L syndrome: a systematic review and meta-analysis. Orphanet J Rare Dis. 2024.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy