Nephropathy Secondary To A Storage Or Other Metabolic Disease C5681622
Kidney damage caused by accumulation of abnormal substances due to inherited metabolic or storage disorders.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Polyuria
(renal)Anemia
(renal)Hypertension
(renal)Hepatosplenomegaly
(hematopoietic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Renal disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Underlying metabolic disease monitoring
Monitoring the primary storage or metabolic disease alongside kidney function to optimize overall disease management.
Treatment of primary metabolic disorder
Disease-specific pharmacotherapy targeting the underlying storage or metabolic disease to reduce renal damage.
Additional treatment options
Metabolic-specific dietary therapy
Dietary modifications specific to the underlying metabolic condition, such as enzyme replacement diets, restricted substrates, or supplementation.
dietaryDialysis for end-stage renal failure
Renal replacement therapy when kidney failure develops secondary to the underlying metabolic disease burden.
procedureActivity modification and energy conservation
Balanced activity program with appropriate rest periods to manage fatigue while maintaining functional capacity.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Nephropathy Secondary To A Storage Or Other Metabolic Disease C5681622?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy