Nephrotic Syndrome Type 2 C1868672
A genetic kidney disorder causing heavy protein loss in urine, swelling, and low blood protein levels.
Key facts at a glance
- ICD-10
- Q63.9
- ICD-11
- LA00.0
- Body system
- renal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Renal vein thrombosis (flank pain, hematuria)
Changes in urination or swelling
(renal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Heavy proteinuria (≥3.5 g/day)
(renal)Peripheral pitting edema
(renal)Hyperlipidemia (elevated cholesterol/triglycerides)
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Corticosteroid therapy
High-dose corticosteroids are typically initiated as first-line immunosuppression to reduce proteinuria and induce remission. Response to steroids guides further treatment duration and intensity.
Renal disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
ACE inhibitors or ARBs
Renin-angiotensin system blockers reduce proteinuria and provide renal protection through blood pressure control and reduction of glomerular pressure. Often used in combination with other therapies.
Additional treatment options
Sodium-restricted diet
Low sodium intake (typically less than 2g daily) helps control edema and reduces fluid retention. Dietary counseling is essential for adherence.
dietaryDiuretic therapy
Loop diuretics and thiazide diuretics may be used short-term to manage significant edema. Response varies based on underlying pathophysiology.
medicationRegular proteinuria monitoring
Frequent monitoring of urine protein levels and serum albumin helps assess disease activity and treatment response. Guides therapeutic decisions.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Nephrotic Syndrome Type 2 C1868672?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Nephrotic Syndrome Type 2 C1868672. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy