Neural Tube Defects X Linked C1845026
A group of birth defects affecting brain and spine development, passed through X-linked inheritance. Severity varies; treatment may include surgery and supportive care.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Hydrocephalus
Chiari malformation type II
Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Spina bifida
(musculoskeletal)Tethered spinal cord syndrome
(neurological)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Surgical neural tube defect repair
Early surgical closure of open neural tube defects is typically performed within the first 24-48 hours of life to minimize infection risk and further neurological damage. The procedure involves careful closure of the defect site.
Ventriculoperitoneal shunt placement
Hydrocephalus commonly associated with neural tube defects often requires CSF shunting to prevent intracranial pressure elevation and brain damage. This diverts cerebrospinal fluid to the abdominal cavity.
Additional treatment options
Rehabilitative physical therapy
Physical therapy focuses on maintaining joint mobility, preventing contractures, and maximizing functional independence. Therapy includes stretching, strengthening, and gait training exercises.
physical_therapyOrthopedic surgical interventions
Surgical correction of limb deformities, clubfoot, or spinal abnormalities associated with neural tube defects may be necessary as the child grows. Procedures include tendon releases, osteotomies, and spinal fusion.
surgicalMultidisciplinary developmental surveillance
Ongoing monitoring by neurology, orthopedics, urology, and developmental specialists ensures comprehensive care addressing all aspects of neural tube defect management.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Neural Tube Defects X Linked C1845026?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Neural Tube Defects X Linked C1845026. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy