Neuropathy Hereditary Sensory Type 2c C3280168
A genetic neuropathy affecting sensory nerves from early childhood. Children born with this condition cannot sense pain or temperature normally.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Osteomyelitis
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Loss of protective pain sensation
(neurologic)Skin ulceration and tissue breakdown
(neurologic)Spontaneous fractures due to sensory loss
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Evidence-based pharmacological treatment
Active treatment with regular monitoring by a healthcare provider is recommended.
Neuropathic Pain Management
Pharmacological management of neuropathic pain using appropriate medications such as certain antidepressants or anticonvulsants as first-line therapy. Regular assessment of pain levels and medication efficacy is essential.
Protective Foot and Skin Care
Comprehensive daily inspection of extremities, wearing protective footwear, and avoiding activities that could cause unnoticed injuries. Patient education on wound prevention is critical given the sensory loss.
Additional treatment options
Physical Therapy and Mobility Support
Therapeutic exercises to maintain joint mobility, muscle strength, and prevent contractures. Gait training and assistive devices may be needed as the condition progresses.
physical_therapyRegular Neurological and Orthopedic Monitoring
Scheduled assessments of sensory function, motor capabilities, and orthopedic complications including fractures and joint abnormalities. Early detection allows for timely intervention.
monitoringNutritional Support for Nerve Health
Balanced diet with adequate B vitamins, antioxidants, and essential nutrients to support overall nerve function and general health. Nutritional counseling may be beneficial.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Neuropathy Hereditary Sensory Type 2c C3280168?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy