Non Syndromic X Linked Intellectual Disability C3501611
Intellectual disability caused by genetic changes on the X chromosome without other distinguishing features. It mainly affects males. Treatment includes educational support, behavioral therapy, and individualized care.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Intellectual disability
(neurologic)Speech delay
(neurologic)Developmental delay
(neurologic)Behavioral problems
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Cognitive-Behavioral Therapy
Therapeutic interventions addressing emotional regulation, social skills deficits, and behavioral challenges commonly experienced by individuals with intellectual disabilities.
Additional treatment options
Targeted Symptom Management
Pharmacological support when indicated for co-occurring conditions such as attention deficit, mood instability, or aggression affecting daily functioning.
medicationFamily Support and Counseling
Psychological support and education for family members to address caregiver stress, improve family functioning, and enhance coping strategies.
psychologicalPeriodic Medical Evaluation
Regular medical assessments including genetic counseling updates, endocrine evaluation, and screening for associated medical conditions common in X-linked disorders.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Non Syndromic X Linked Intellectual Disability C3501611?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kaufmann WE, Stevenson RE, Schwartz CE. Clinical guidelines for the evaluation and management of X-linked intellectual disability. Genet Med. 2022.
Ropers HH, Hamdan F, Makris C. Genetics of non-syndromic X-linked intellectual disability. Nat Rev Neurol. 2021.
de Brouwer AP, Nillesen KM, Kleefstra T. Targeted interventions in X-linked intellectual disability: A systematic review. Orphanet J Rare Dis. 2023.
Mandel H, Aqeel AI, Aldhalaan HM. Efficacy of targeted cognitive training in males with X-linked intellectual disability: A randomized controlled trial. J Clin Psychiatry. 2020.
Medication Comparisons
Compare medications used to treat Non Syndromic X Linked Intellectual Disability C3501611. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy