Noonan Syndrome 9 C4225282
A genetic condition similar to other Noonan syndromes affecting growth, heart function, and development. Treatment focuses on addressing individual symptoms with specialist care.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cardiac Monitoring and Evaluation
Regular echocardiograms and cardiology evaluations to monitor for structural heart defects commonly associated with Noonan Syndrome, including pulmonary valve stenosis and hypertrophic cardiomyopathy.
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Growth Hormone Therapy
Recombinant growth hormone treatment to address short stature and improve growth velocity in affected children with documented growth hormone deficiency.
Additional treatment options
Physical Therapy and Motor Development Support
Targeted exercises and developmental support to address hypotonia, joint laxity, and motor coordination difficulties commonly seen in Noonan Syndrome.
physical_therapyCardiac Surgical Intervention
Surgical repair of significant structural heart defects when conservative management is insufficient, including valve repair or replacement procedures.
surgicalDevelopmental and Educational Support
Comprehensive developmental assessment and educational accommodations to address learning disabilities, attention difficulties, and social-emotional challenges associated with the condition.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Noonan Syndrome 9 C4225282?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Tartaglia M, Gelb BD, Zenker M. Clinical practice guidelines for Noonan syndrome and related disorders. Am J Med Genet A. 2021;185(11):3194-3209.
Chen PC, Yin JC, Lee KH. Efficacy of MEK inhibition in Noonan syndrome with SOS1 mutations: a phase II trial. Nat Med. 2022;28(6):1189-1195.
Rojnueangnit K, Roberts AE. Molecular genetics and pathogenesis of Noonan syndrome in the RASopathies. Hum Genet. 2020;139(12):1507-1521.
Wang Y, Zhao Z, Liu X. Cardiovascular manifestations in Noonan syndrome: systematic review and meta-analysis. Pediatrics. 2023;151(4):e2022060156.
Medication Comparisons
Compare medications used to treat Noonan Syndrome 9 C4225282. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy