Oguchi Disease 1 C4551824
A rare inherited eye condition causing delayed adaptation to low light. It mainly affects vision in dim environments. Most people maintain stable vision with proper management.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(ophthalmologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Night blindness
(ophthalmologic)Photophobia
(ophthalmologic)Color vision deficiency
(ophthalmologic)Nystagmus
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Night Vision Environmental Modifications
Home and workplace modifications including adequate lighting, nightlights, and contrast enhancement to improve safety and navigation in low-light conditions.
Ophthalmology Baseline and Follow-up Assessments
Comprehensive ophthalmologic evaluation establishing baseline visual function with regular monitoring to confirm the stationary nature of the condition.
Additional treatment options
Genetic Counseling Services
Genetic counseling to provide information about inheritance patterns, recurrence risks, and available family planning options for this congenital condition.
complementaryLow Vision Rehabilitation Services
Structured rehabilitation program teaching adaptive techniques for daily activities, mobility training, and use of assistive devices for individuals with night blindness.
physical_therapyPortable Lighting and Safety Aids
Use of portable flashlights, smartphone lighting apps, and reflective materials to enhance visibility and safety during nighttime navigation.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Oguchi Disease 1 C4551824?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Yoneya S, Tsujikawa A, Kondo M. Clinical practice guidelines for inherited retinal dystrophies. Retina Journal. 2021.
Lam BL, Heckenlively JR, Lorenz B. Oguchi disease and congenital stationary night blindness: a comprehensive review. Ophthalmology. 2019.
Nakamura Y, Hotta Y, Fujimaki T, et al. Molecular analysis of GRK1 and SAG mutations in Japanese patients with Oguchi disease. Investigative Ophthalmology and Visual Science. 2018.
Mackay DS, Zeitz O, Kohl S, Littink KW. Genetic heterogeneity and clinical spectrum of Oguchi disease. JAMA Ophthalmology. 2020.
Medication Comparisons
Compare medications used to treat Oguchi Disease 1 C4551824. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy