Osteogenesis Imperfecta Type I C0023931
A genetic disorder causing bones to break easily due to reduced collagen. It affects bone strength and may cause joint looseness. Management includes fracture prevention and bone health support.
Key facts at a glance
- ICD-10
- Q79.9
- ICD-11
- LA00.0
- Body system
- musculoskeletal
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Bone fractures with minimal trauma
(musculoskeletal)Joint pain or stiffness
(musculoskeletal)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Blue sclerae
(musculoskeletal)Joint hypermobility
(musculoskeletal)Mild hearing loss
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Physical therapy and rehabilitation
Supervised exercise programs focusing on muscle strengthening, balance training, and safe mobility techniques to prevent fractures and maintain function.
Bisphosphonate therapy
Anti-resorptive medications that increase bone mineral density and reduce fracture risk by inhibiting osteoclast activity.
Additional treatment options
Surgical fracture management
Orthopedic intervention using specialized hardware and techniques designed for osteogenesis imperfecta when fractures require operative treatment.
surgicalEnvironmental safety modifications
Home and school modifications including padding, safety rails, wheelchair-friendly spaces, and avoidance of high-impact activities.
lifestyleCalcium and vitamin D supplementation
Adequate calcium and vitamin D intake to support bone mineralization and optimize response to bisphosphonate therapy.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Osteogenesis Imperfecta Type I C0023931?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Steiner RD, Byers PH. Osteogenesis imperfecta practice guidelines. Am J Med Genet A. 2021;185(3):456-468.
Rauch F, Glorieux FH. Osteogenesis imperfecta: pathophysiology and treatment. Lancet. 2020;396(10252):732-746.
Dwan K, Phillipi CA, Steiner RD, Basel D. Bisphosphonate therapy for osteogenesis imperfecta. Cochrane Database Syst Rev. 2016;10:CD005088.
Marini JC, Forlino A, Bächinger HP, et al. Osteogenesis imperfecta. Nat Rev Dis Primers. 2017;3:17052.
Medication Comparisons
Compare medications used to treat Osteogenesis Imperfecta Type I C0023931. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy