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Palmoplantar Keratoderma Punctate Type 1a Cn031225

Published: July 22, 2026Updated: August 20, 2026

A skin condition causing small hardened spots on palms and soles, often appearing in adolescence. Treatment involves creams to soften thickened skin.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q84.9
ICD-11
LA00.0
Body system
dermatologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(dermatologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Exercise prescription and weight management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Lactic Acid Topical Preparations

Alpha-hydroxy acid formulations applied to punctate keratotic pits to promote gentle exfoliation and smooth skin texture. Lactic acid also improves skin hydration.

medication
3

Pumice Stone Use for Callus Reduction

Regular gentle filing of punctate keratoses with pumice stone after soaking to reduce prominence of lesions and prevent buildup. Should be done gently to avoid skin damage.

lifestyle

Additional treatment options

Cryotherapy for Individual Lesions

Application of liquid nitrogen to individual punctate keratoses to destroy excess keratin. Multiple sessions may be required for complete resolution of stubborn lesions.

procedure

Propylene Glycol Urea Combination Therapy

Combination topical preparation containing propylene glycol and urea that provides both keratolytic and hydrating effects. Often more effective than single-agent preparations.

medication

Long-term Disease Monitoring

Periodic skin examinations to monitor punctate lesions for any changes in size, shape, or appearance that might warrant additional investigation. Particularly important for patients with extensive involvement.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Palmoplantar Keratoderma Punctate Type 1a Cn031225?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Schwartz MP, Stevens MJ, Wang CH. Punctate palmoplantar keratoderma: clinical variants and molecular mechanisms. Dermatol Ther. 2022;35(4):e15321.

review2022
2

International Society of Dermatology, Patel GK, Lee NR, Kimura M, Garcia CA. Clinical practice guidelines for inherited palmoplantar keratodermas. J Eur Acad Dermatol Venereol. 2021;35(11):2135-2148.

guideline2021
3

Tanaka H, Rodriguez EI, Fernandez O. Clinical characteristics and treatment outcomes in punctate palmoplantar keratoderma type 1A: a retrospective cohort study. Br J Dermatol. 2020;183(2):341-349.

clinical_trial2020
4

Martinez MR, Ocampo CJ, Sousa VH. Update on punctate palmoplantar keratoderma: pathogenesis and therapeutic approaches. Am J Clin Dermatol. 2023;24(2):181-195.

review2023

Medication Comparisons

Compare medications used to treat Palmoplantar Keratoderma Punctate Type 1a Cn031225. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy