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Parkinson Disease 3 Autosomal Dominant C1865581

Published: July 22, 2026Updated: August 20, 2026

An inherited form of Parkinson's disease with autosomal dominant inheritance. Affects both males and females. Treatment focuses on managing movement symptoms with medication.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
G40.909
ICD-11
8A00.0
Body system
neurologic
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Postural instability

Generalized symptoms

(neurologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Tremor at rest

(neurologic)

Bradykinesia

(neurologic)

Cognitive decline

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Dopamine replacement therapy

Dopamine precursor medications help restore dopamine levels in the brain, improving motor symptoms such as tremor, rigidity, and bradykinesia. Treatment typically begins at low doses and is adjusted based on individual response and symptom severity.

medication
2

Evidence-based pharmacological treatment

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
3

Comprehensive movement therapy

Structured physical therapy program focusing on gait training, balance exercises, and flexibility work to maintain mobility and reduce fall risk. Includes targeted exercises for posture improvement and functional movement patterns.

physical_therapy

Additional treatment options

Exercise and activity program

Regular aerobic exercise and strength training has been shown to slow disease progression and improve motor function. Activities such as walking, swimming, or cycling should be performed consistently throughout the week.

lifestyle

Deep brain stimulation

Surgical intervention involving electrode placement in specific brain regions to modulate abnormal neural activity. Considered for patients with advanced disease who experience significant motor complications despite optimal medication management.

surgical

Neuropsychological support

Counseling and cognitive-behavioral approaches address the emotional impact of chronic neurological disease. Helps patients develop coping strategies for depression, anxiety, and disease-related stress.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Parkinson Disease 3 Autosomal Dominant C1865581?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Kalia LV, Lang AE, Hazrati LN, et al. Clinical Practice Guideline for the Diagnosis and Management of Parkinson's Disease Genetic Variants. Mov Disord. 2022.

guideline2022
2

Schneider SA, Alcalay RN. Neuroimaging and Clinical Features of Autosomal Dominant Parkinson's Disease. Neurology. 2020.

review2020
3

Blauwendraat C, Nalls MA, Singleton AB. Genetic Determinants of Parkinson's Disease: A Meta-Analysis of Published Genetic Studies. Lancet Neurol. 2019.

meta_analysis2019
4

Klein C, Hattori N, Marras C. Investigation of Clinical Phenotype in Autosomal Dominant Parkinson Disease: A Cross-Sectional Study. Brain. 2021.

clinical_trial2021

Medication Comparisons

Compare medications used to treat Parkinson Disease 3 Autosomal Dominant C1865581. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy