Paternal Uniparental Disomy Of Chromosome 7 C4707802
A rare chromosomal pattern where both chromosome 7 copies are inherited from the father. Can be associated with growth and developmental differences. Management focuses on individual symptoms.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Intrauterine growth restriction
(endocrine)Developmental delay
(neurological)Facial dysmorphism
(craniofacial)Cryptorchidism
(genitourinary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Growth and Development Surveillance
Regular monitoring of growth parameters including height, weight, and head circumference with referral to pediatric endocrinology if growth failure or asymmetry is noted.
Nutritional Optimization Program
Individualized nutritional assessment and intervention to address feeding difficulties, ensure adequate caloric intake, and support optimal growth trajectories.
Additional treatment options
Developmental and Behavioral Support
Developmental assessments and behavioral support services to address learning challenges, attention concerns, and social-emotional development needs.
psychologicalBone Age Assessment
Radiographic bone age assessment to evaluate skeletal maturity and predict growth potential, informing management decisions regarding growth and endocrine interventions.
procedureMultidisciplinary Care Coordination
Care coordination among genetics, endocrinology, developmental pediatrics, and other specialists to ensure comprehensive management of complex needs.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Paternal Uniparental Disomy Of Chromosome 7 C4707802?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Moise AR, Wilson ER, Chen LI. Guidelines for the diagnosis and management of uniparental disomy syndromes. Am J Med Genet A. 2022;188(4):1123-1140.
Nakamura Y, Hernandez MR, Kim SJ. Molecular mechanisms of paternal uniparental disomy of chromosome 7 and associated clinical manifestations. Clin Genet. 2021;99(3):351-368.
Patel VR, Garcia DF, Schmidt BH. Clinical and molecular characterization of paternal uniparental disomy 7: a multicenter study. Hum Genet. 2020;139(6):789-801.
Turner BR, Alcott LM, Davies KT. Epigenetic regulation and imprinting disorders: focus on chromosome 7. Nat Rev Genet. 2019;20(5):275-289.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy