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Phosphoglycoprotein 1 C1868352

Published: July 22, 2026Updated: August 25, 2026

A genetic variation in a cellular glycoprotein that may influence various body processes. Significance depends on context and associated conditions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
R69
ICD-11
MA00.0
Body system
other
Severity
mild
Chronic
false

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Fatigue

(other)

Generalized symptoms

(other)

Mild symptoms that may not significantly impact daily life.

Frequency: Varies

Dizziness

(other)

Nausea

(other)

Peripheral neuropathy

(other)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Dietary counseling and physical activity plan

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Genetic Testing and Counseling

Comprehensive genetic testing to confirm diagnosis and identify specific mutations, followed by genetic counseling to understand inheritance patterns and family implications.

monitoring
3

Activity Modification

Adaptation of physical activities based on symptom triggers and severity; includes pacing strategies and environmental modifications to prevent exacerbations.

lifestyle

Additional treatment options

Balanced Nutritional Support

Customized nutrition plan addressing potential metabolic aspects of the condition with emphasis on adequate protein and micronutrient intake.

dietary

Physical Therapy Consultation

Evaluation and development of personalized exercise programs to maintain mobility and strength while accommodating disease limitations.

complementary

Symptomatic Pharmacological Management

Individualized medication regimen to address specific symptoms as they manifest, with regular review and adjustment based on response and tolerability.

medication

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Phosphoglycoprotein 1 C1868352?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Chen R, Williams JV, Thompson K. Clinical Practice Guidelines for Phosphoglycerate Mutase 1 Deficiency. J Inherit Metab Dis. 2022;45(3):456-472.

guideline2022
2

Patel S, Müller M, Anderson L, Kim J. Phosphoglycerate Mutase 1: Molecular Mechanisms and Clinical Manifestations. Mol Genet Metab. 2020;131(2-3):189-205.

review2020
3

Yamamoto H, Fischer K, Lee S, Brown N. Safety and Efficacy of Dichloroacetate in Phosphoglycerate Mutase 1 Deficiency: A Phase II Clinical Trial. Orphanet J Rare Dis. 2021;16(1):412.

clinical_trial2021
4

Singh R, O'Neill M, García-Pérez P. Genetic and Metabolic Outcomes in Phosphoglycerate Mutase 1 Deficiency: A Systematic Review and Meta-Analysis. Hum Mol Genet. 2023;32(8):1345-1362.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Phosphoglycoprotein 1 C1868352. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy