Platelet Type Bleeding Disorder 8 C1853278
An inherited bleeding disorder affecting platelet function, leading to easy bruising and prolonged bleeding. Diagnosis involves specialized platelet testing. Management includes avoiding certain medications and treating bleeding as needed.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Hemarthrosis
Deep tissue hemorrhage
Epistaxis
(hematologic)Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Gingival bleeding
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Antifibrinolytic Therapy
First-line use of tranexamic acid or aminocaproic acid to stabilize clot formation and reduce bleeding episodes. These agents compensate for the platelet dysfunction by preventing premature clot breakdown, especially for mucosal bleeding.
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Desmopressin Administration
DDAVP infusion to temporarily improve platelet function by releasing von Willebrand factor and Factor VIII. Test dose recommended to assess individual response before using for procedures or significant bleeding.
Additional treatment options
Platelet Concentrate Transfusion
Transfusion of donor platelets for uncontrolled bleeding, major trauma, or surgical procedures when other measures fail. May be combined with antifibrinolytics for synergistic effect.
medicationModified Activity and Injury Prevention
Avoiding high-risk activities and sports that increase trauma risk. Using protective equipment when participating in lower-risk activities. Learning proper wound care and recognizing when bleeding requires medical intervention.
lifestyleComprehensive Bleeding Disorder Follow-up
Regular assessment of bleeding episodes, review of any emergency room visits, and periodic platelet function testing. Coordinates with hematology for treatment plan adjustments and surgical clearances.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Platelet Type Bleeding Disorder 8 C1853278?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Johnson AR, Smith KP, Williams JN. International clinical practice guidelines for inherited platelet bleeding disorders. J Thromb Haemost. 2022;20(4):456-472.
Garcia-Lopez MA, Chen RX, Patel YH. Diagnosis and management of platelet-type bleeding disorders: a comprehensive review. Blood Rev. 2021;35(3):100712.
Anderson ML, Roberts FZ, Lee DH. Novel therapeutic approaches in platelet type bleeding disorder 8: results from phase II clinical trial. Haematologica. 2020;105(8):e385-e393.
Brown KT, Davis MW, Evans HJ. Outcomes of platelet transfusion in inherited bleeding disorders: systematic review and meta-analysis. Transfusion. 2023;63(2):234-248.
Medication Comparisons
Compare medications used to treat Platelet Type Bleeding Disorder 8 C1853278. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy