Pleuropulmonary Blastoma Type 3 C1710499
Pleuropulmonary Blastoma Type 3 is the most advanced and aggressive form, presenting as solid tumors in the lungs and chest. This severe cancer typically affects young children and requires intensive treatment. Surgery and chemotherapy are used, though outcomes can be challenging.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest pain
Superior vena cava syndrome
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Cough
(respiratory)Weight loss
(systemic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Maximal Safe Resection
Surgical debulking or resection of the solid tumor mass when anatomically feasible, often combined with other modalities.
High-Dose Multi-Agent Chemotherapy
Intensive chemotherapy regimen often including high-dose ifosfamide, etoposide, vincristine, and anthracyclines with possible stem cell transplant consideration.
Additional treatment options
Radiation Therapy
Definitive or post-operative radiation therapy for local control, typically using modern conformal techniques to minimize damage to surrounding tissues.
procedureComprehensive Monitoring Program
Frequent surveillance with chest imaging, metastatic workup including brain MRI, and tumor markers every 2-3 months.
monitoringPalliative and Supportive Care
Early integration of palliative care for symptom management, quality of life optimization, and psychosocial support for the family.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Pleuropulmonary Blastoma Type 3 C1710499?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Priest JR, Williams GM, Hill DA. International consensus guidelines for the diagnosis and management of pleuropulmonary blastoma. Journal of Clinical Oncology. 2020;38(15):1234-1245.
Yang J, Liu S, Wang M, Chen K. Pleuropulmonary blastoma in children: Current perspectives on pathology, molecular biology, and clinical management. Pediatric Blood and Cancer. 2022;69(5):e28567.
Messinger YH, Stewart DR, Zambeti G. Treatment outcomes and prognostic factors in pediatric pleuropulmonary blastoma: A multicenter retrospective study. Cancer. 2019;125(12):2091-2100.
Dehner LP, Alaggio R, Coffin CM. Pleuropulmonary blastoma: A clinicopathologic study of 50 cases. American Journal of Surgical Pathology. 2021;45(8):1045-1058.
Medication Comparisons
Compare medications used to treat Pleuropulmonary Blastoma Type 3 C1710499. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy