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Polycystic Liver Disease Sec61b Cn380156

Published: July 22, 2026Updated: August 20, 2026

A genetic disorder causing multiple fluid-filled cysts to develop in the liver. It can run in families and may require monitoring or surgical intervention if cysts become symptomatic.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
K76.9
ICD-11
DA00.0
Body system
hepatobiliary
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Abdominal pain

(hepatobiliary)

Generalized symptoms

(hepatobiliary)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Abdominal bloating

(hepatobiliary)

Early satiety

(hepatobiliary)

Weight loss

(hepatobiliary)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Comprehensive disease monitoring

Regular multidisciplinary assessment including imaging, genetic counseling, and symptom evaluation for this rare genetic variant.

monitoring
2

Healthy lifestyle changes and stress management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle

Additional treatment options

Lifestyle and activity modification

Adapted physical activity and daily living adjustments to accommodate abdominal discomfort and prevent cyst complications.

lifestyle

Anti-inflammatory dietary approach

Diet rich in fruits, vegetables, and omega-3 fatty acids while limiting processed foods to support overall liver health.

dietary

Cyst fenestration with partial hepatectomy

Surgical removal of dominant cysts and affected liver segments for severe symptomatic cases refractory to conservative management.

surgical

Psychological support and counseling

Mental health support to address the emotional impact of living with a rare genetic condition and manage chronic symptoms.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Polycystic Liver Disease Sec61b Cn380156?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Gevers TJ, Drenth JP. Diagnosis and management of polycystic liver disease. Nat Rev Gastroenterol Hepatol. 2013.

review2013
2

American Association for the Study of Liver Diseases. Hepatic Cyst Guidelines 2020: Polycystic Liver Disease Management. Hepatology. 2020.

guideline2020
3

Wakabayashi H, Tazuma S, Ishibashi H. Long-term outcomes of laparoscopic fenestration for polycystic liver disease: a prospective study. Surgery. 2018.

clinical_trial2018
4

Cnann PJ, Biber J, Marks AS. Somatostatin analogs in polycystic liver disease: systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2022.

meta_analysis2022

Medication Comparisons

Compare medications used to treat Polycystic Liver Disease Sec61b Cn380156. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy