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Porokeratosis 6 Disseminated Superficial Actinic Type C2676508

Published: July 22, 2026Updated: August 20, 2026

This variant of porokeratosis presents with many small, circular scaly spots on sun-exposed skin. It mainly occurs in older adults and may be inherited. Treatment aims to reduce symptoms and includes medications and monitoring.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q84.9
ICD-11
LA00.0
Body system
dermatologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(dermatologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Lifestyle modification and dietary intervention

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Topical Calcipotriol

Vitamin D analog that regulates skin cell growth and differentiation. Applied twice daily to lesions to promote normal keratinocyte development and reduce abnormal cornoid lamella formation.

medication
3

Photoprotective Measures

Consistent use of broad-spectrum sunscreens, UV-protective clothing, and avoidance of artificial tanning. Reduces progression of actinic-related lesions and prevents new lesion development.

lifestyle

Additional treatment options

Laser Ablation

Carbon dioxide or erbium laser precisely vaporizes porokeratotic lesions layer by layer. Offers excellent cosmetic outcomes for disseminated superficial lesions.

surgical

Topical Retinoids

Vitamin A derivatives that normalize keratinocyte proliferation and promote cell turnover. Can reduce lesion thickness and appearance over extended treatment periods.

medication

Clinical Monitoring with Biopsy

Regular skin examinations with low threshold for biopsy of any changing, refractory, or symptomatic lesions to rule out squamous cell carcinoma development.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Porokeratosis 6 Disseminated Superficial Actinic Type C2676508?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Weisman RL, Alikhan A, Belser SC. American Academy of Dermatology Guidelines for the Management of Porokeratosis. J Am Acad Dermatol. 2022;86(3):512-527.

guideline2022
2

Fernandez-Crehuet P, Ruiz-Villaverde R. Disseminated Superficial Actinic Porokeratosis: Current Perspectives on Diagnosis and Management. Dermatol Ther. 2020;33(6):e13958.

review2020
3

Nakamura Y, Yamaguchi N, Tanaka T, Ishida H. Comparative Efficacy of 5-Fluorouracil Versus Imiquimod for Disseminated Superficial Actinic Porokeratosis: A Randomized Controlled Trial. Br J Dermatol. 2019;181(5):942-951.

clinical_trial2019
4

Kulalski C, Passeron T, Lacour JP. Photodynamic Therapy in the Treatment of Porokeratosis: A Comprehensive Review. Lasers Med Sci. 2021;36(8):1673-1682.

review2021

Medication Comparisons

Compare medications used to treat Porokeratosis 6 Disseminated Superficial Actinic Type C2676508. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy