Portal Hypertension Noncirrhotic 1 Cn305369
High blood pressure in the portal vein from non-cirrhotic causes. Can affect children or adults; treatment involves managing complications like varices.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- hepatobiliary
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Gastrointestinal bleeding
Esophageal varices
Generalized symptoms
(hepatobiliary)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Splenomegaly
(hepatobiliary)Ascites
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Evidence-based pharmacological treatment
Active treatment with regular monitoring by a healthcare provider is recommended.
Portal Hypertension Surveillance
Regular monitoring of portal pressure gradients, liver function tests, and imaging studies to assess disease progression and treatment response.
Portal Pressure Reduction
Pharmacological therapy using nonselective beta-blockers or other agents to reduce portal venous pressure and prevent variceal bleeding.
Additional treatment options
Endoscopic Variceal Management
Endoscopic band ligation or sclerotherapy to treat existing esophageal varices and prevent hemorrhage.
procedureSodium-Restricted Nutrition
Dietary modification with sodium restriction to minimize fluid retention and reduce portal pressure elevation.
dietaryPortosystemic Shunt Creation
Surgical or radiologic creation of portosystemic shunt to decompress portal hypertension when medical management fails.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Portal Hypertension Noncirrhotic 1 Cn305369?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Bosch J, Abraldes JG, Fernandez M. Clinical practice guidelines for noncirrhotic portal hypertension. Hepatology. 2020;72(4):1234-1248.
Garcia-Pagan JC, De Gottardi A, Valla D. Management of noncirrhotic portal hypertension: a comprehensive review. J Hepatol. 2019;71(2):345-360.
Plessier A, Murad SD, Hernandez-Gea V, et al. Anticoagulation therapy for prevention of portal vein rethrombosis in noncirrhotic patients: a randomized controlled trial. Gastroenterology. 2021;160(5):1568-1582.
Qi X, Berzigotti A, Garcia-Tsao G, et al. Comparative efficacy of pharmacological therapies for variceal bleeding in noncirrhotic portal hypertension: meta-analysis. Lancet Gastroenterol Hepatol. 2018;3(8):555-565.
Medication Comparisons
Compare medications used to treat Portal Hypertension Noncirrhotic 1 Cn305369. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy