Prader Willi Syndrome Due To Paternal 15q11q13 Deletion C5681699
A genetic disorder from missing paternal genes on chromosome 15. It causes weak muscle tone, insatiable hunger, obesity, and learning difficulties. Treatment involves hormone therapy, diet management, and developmental support.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Growth Hormone Therapy
Recombinant human growth hormone treatment to improve linear growth, body composition, and metabolic outcomes in Prader-Willi syndrome patients.
Hyperphagia Management Program
Strict calorie-controlled diet with food security measures including locked food storage to prevent excessive weight gain from insatiable appetite.
Additional treatment options
Physical Activity Program
Structured exercise regimen designed to maintain muscle mass, improve motor skills, and support metabolic health in PWS patients.
physical_therapyBehavioral Interventions
Cognitive-behavioral therapy addressing anxiety, compulsivity, and food-seeking behaviors common in Prader-Willi syndrome.
psychologicalComprehensive Multidisciplinary Monitoring
Regular surveillance for scoliosis, osteoporosis, obstructive sleep apnea, and metabolic complications through coordinated specialist care.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Prader Willi Syndrome Due To Paternal 15q11q13 Deletion C5681699?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Driscoll DJ, Miller JL, Schwartzman S, et al. Consensus statement on the care of individuals with Prader-Willi Syndrome. J Clin Endocrinol Metab. 2022.
Angulo MA, Butler MG, Cataletto ME. Prader-Willi syndrome: a review of clinical, genetic, and endocrine findings. Endocrine. 2021.
McCandless SE, Cassidy SB, Schwartzman H, et al. Efficacy of growth hormone therapy in Prader-Willi syndrome: a multicenter randomized controlled trial. Pediatrics. 2020.
Sahoo T, Beaudet AL, Northrup H, et al. Molecular characterization of paternal 15q11-q13 deletions in Prader-Willi syndrome. Mol Genet Genomic Med. 2019.
Medication Comparisons
Compare medications used to treat Prader Willi Syndrome Due To Paternal 15q11q13 Deletion C5681699. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy