Premature Ovarian Failure 6 C2676742
Premature Ovarian Failure 6 is an inherited condition where ovarian function declines before age 40. Management involves hormone replacement therapy and fertility counseling.
Key facts at a glance
- ICD-10
- E34.9
- ICD-11
- 5A00.0
- Body system
- endocrine
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(endocrine)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Secondary amenorrhea
(endocrine)Hot flashes
(endocrine)Infertility
(endocrine)Night sweats
(endocrine)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Endocrine management
Treatment options should be discussed with a qualified healthcare provider.
Hormone Replacement Therapy
Estrogen and progesterone replacement to compensate for ovarian hormone deficiency and manage symptoms. Typically administered as oral tablets, patches, or topical gels.
Calcium and Vitamin D Supplementation
Daily supplementation to prevent bone density loss associated with estrogen deficiency. Calcium supports bone mineralization while vitamin D enhances calcium absorption.
Additional treatment options
Weight-Bearing Exercise Program
Regular participation in weight-bearing activities such as walking, resistance training, or stair climbing to maintain bone density and cardiovascular health.
lifestylePsychological Counseling and Support
Individual or group therapy addressing emotional impact including grief, fertility concerns, and body image issues. Provides coping strategies for managing a chronic condition.
psychologicalBone Density Monitoring
Regular dual-energy X-ray absorptiometry scans to assess bone mineral density and detect early osteopenia or osteoporosis.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Premature Ovarian Failure 6 C2676742?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
European Society of Human Reproduction and Embryology. ESHRE Guideline on Management of Women with Premature Ovarian Insufficiency. Hum Reprod. 2016.
Nelson LM. Primary Ovarian Insufficiency. N Engl J Med. 2009;360(6):606-614.
Tosh D, Khan R. Hormone Therapy Outcomes in Premature Ovarian Insufficiency: A Systematic Review and Meta-Analysis. J Clin Endocrinol Metab. 2022;107(8):2318-2329.
Mackay DR, Walsh K. Genetic Causes of Primary Ovarian Insufficiency. Clin Obstet Gynecol. 2020;63(4):687-706.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy