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Primary Ciliary Dyskinesia 5 C1837615

Published: July 22, 2026Updated: August 25, 2026

A genetic condition where tiny hair-like structures called cilia don't work properly, causing chronic lung infections and breathing issues. Treatment focuses on clearing airways and managing infections.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
J98.9
ICD-11
CA00.0
Body system
respiratory
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Hemoptysis

Shortness of breath or cough

(respiratory)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Chronic productive cough

(respiratory)

Recurrent sinusitis

(respiratory)

Bronchiectasis

(respiratory)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Environmental Control and Avoidance

Implementation of measures to reduce exposure to respiratory irritants including tobacco smoke, air pollution, and occupational dusts that can exacerbate ciliary dysfunction.

lifestyle
2

Respiratory therapy and management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

High-Frequency Chest Wall Oscillation Therapy

Use of oscillatory positive pressure devices such as vest therapy to create rapid vibrations that help dislodge mucus from airway walls for easier expectoration.

physical_therapy

Additional treatment options

Nasal Corticosteroid Sprays

Topical nasal steroid medications to reduce inflammation in the nasal passages and sinuses, decreasing mucosal edema and improving sinus drainage.

medication

Nasal Saline Irrigation

Regular nasal irrigation with saline solutions using squeeze bottles or neti pots to mechanically clear nasal passages and sinuses of accumulated mucus and debris.

procedure

Audiological Monitoring

Regular hearing tests and ear examinations to monitor for chronic otitis media with effusion and sensorineural hearing loss secondary to recurrent infections.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Primary Ciliary Dyskinesia 5 C1837615?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Shapiro AJ, Davis SD, Ferkol T, Dell SD, Rosenstein BJ, Leigh MW.ERS Guidelines for the Diagnosis and Management of Primary Ciliary Dyskinesia.European Respiratory Journal. 2021;57(6):2002429.

guideline2021
2

Knowles MR, Daniels LA, Davis SD, Zariwala MA, Leigh MW.Genetic Basis of Primary Ciliary Dyskinesia: Mutations in DNAH5 and Other Dynein Genes.American Journal of Respiratory and Critical Care Medicine. 2020;201(5):607-619.

clinical_trial2020
3

Lucas JS, Walker WT, Hogg C, et al.Clinical Manifestations and Diagnosis of Primary Ciliary Dyskinesia in Children and Adults.Lancet Respiratory Medicine. 2019;7(5):438-452.

review2019
4

Raidt J, Werner C, Olbrich H, et al.Treatment Outcomes in Primary Ciliary Dyskinesia: A Systematic Review and Meta-Analysis.Chest. 2022;161(4):1055-1070.

meta_analysis2022

Medication Comparisons

Compare medications used to treat Primary Ciliary Dyskinesia 5 C1837615. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy