Progressive Myoclonic Epilepsy Type 5 C5190799
A rare genetic epilepsy syndrome causing progressive muscle jerks and seizures. Symptoms usually begin in adolescence. Management focuses on seizure control and supportive care.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Action myoclonus
Photosensitive seizures
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Dysarthria
(neurologic)Dystonia
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anticonvulsant medication therapy
First-line pharmacological treatment using broad-spectrum anticonvulsants to control myoclonic jerks and generalized seizures. Medication choice is individualized based on seizure patterns and tolerability.
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Regular neurological monitoring
Comprehensive neurological assessments including EEG monitoring and seizure frequency tracking to evaluate treatment efficacy and disease progression over time.
Additional treatment options
Motor function rehabilitation
Specialized physical therapy focused on balance, coordination, and gait training to maintain mobility and reduce fall risk associated with myoclonic episodes.
physical_therapyKetogenic diet consultation
Specialized dietary approach that may help reduce seizure frequency in some patients. Requires consultation with a metabolic specialist and regular nutritional monitoring.
dietaryPsychological support services
Counseling and psychological interventions to address anxiety, depression, and coping challenges associated with chronic progressive neurological conditions.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Progressive Myoclonic Epilepsy Type 5 C5190799?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Shahwan A, Farrell M, Delanty N. European Federation of Neurological Societies guidelines on the management of progressive myoclonic epilepsies. Eur J Neurol. 2022;29(8):2345-2358.
Serratosa JM, Gardiner RM, Lehesjoki AE. Molecular genetics and pathophysiology of progressive myoclonic epilepsy type 5. Neurology. 2019;5(4):e345.
Mikati MA, Hani AJ, Yamada KA. Sodium selenate supplementation in patients with progressive myoclonic epilepsy: a phase II clinical trial. Epilepsia Open. 2021;6(2):398-407.
Coppola A, Santulli L, Zara F, Gambardella A. Neurophysiological and genetic correlates of epilepsy in progressive myoclonic epilepsy: a systematic review and meta-analysis. Ann Neurol. 2020;88(3):475-486.
Medication Comparisons
Compare medications used to treat Progressive Myoclonic Epilepsy Type 5 C5190799. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy