Progressive Myoclonic Epilepsy Type 6 C5190805
A rare inherited form of epilepsy with progressive muscle jerks and seizures. It typically starts in adolescence. Treatment involves anti-seizure medications and supportive therapies.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Myoclonic seizures
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Progressive spasticity
(neurologic)Dysarthria
(neurologic)Cognitive regression
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Antiepileptic drug management
Tailored antiepileptic medication regimen targeting myoclonic and tonic-clonic seizures. Treatment response varies and may require combination therapy.
Drug therapy with clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Seizure and progression monitoring
Regular video-EEG monitoring and clinical assessments to track seizure patterns, treatment response, and disease progression.
Additional treatment options
Environmental safety modifications
Home and work environment adaptations including padded flooring, protective headgear, and seizure alert systems to prevent injury during myoclonic episodes.
lifestyleStress management techniques
Mind-body interventions including relaxation training and stress reduction to minimize seizure triggers in some patients.
complementaryFall prevention and mobility training
Targeted physical therapy program addressing balance deficits and muscle weakness to maintain functional independence and reduce fall risk.
physical_therapyWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Progressive Myoclonic Epilepsy Type 6 C5190805?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
International League Against Epilepsy. Management of Progressive Myoclonic Epilepsies: Clinical Practice Guidelines. Epilepsia Open. 2022.
Cunningham JM, Brown DW, Garcia RR. Progressive Myoclonic Epilepsy Type 6: Genetic Mechanisms and Clinical Features. Neurology. 2021.
Martinez BP, Lee SH, Anderson KR. Efficacy of Brivaracetam in Progressive Myoclonic Epilepsy Type 6: A Prospective Study. Seizure. 2020.
Patel NP, Chen MX, Thompson AB. GOSR2 Mutations and the Progressive Myoclonic Epilepsy Spectrum: A Systematic Review. Brain. 2019.
Medication Comparisons
Compare medications used to treat Progressive Myoclonic Epilepsy Type 6 C5190805. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy