Progressive Myoclonic Epilepsy Type 7 C4015420
A rare genetic epilepsy causing myoclonic seizures and progressive neurological decline, typically beginning in childhood. Treatment focuses on seizure control and supportive care.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Myoclonic seizures
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Cerebellar ataxia
(neurologic)Behavioral changes
(neurologic)Peripheral neuropathy
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up care
Active treatment with regular monitoring by a healthcare provider is recommended.
Myoclonus-specific medication
Targeted pharmacological approach focusing on medications with specific anti-myoclonic properties such as clonazepam or levetiracetam to control involuntary muscle jerks.
Diagnostic evaluation for surgical candidacy
Comprehensive pre-surgical evaluation including advanced neuroimaging and video-EEG monitoring to determine if resective surgery or neurostimulation is appropriate.
Additional treatment options
Neuropsychological support
Cognitive assessment and rehabilitation to address progressive cognitive decline and provide strategies for maintaining cognitive function.
psychologicalLow glycaemic index diet
Modified carbohydrate intake to provide metabolic support for neuronal function while avoiding extreme dietary restrictions.
dietarySleep hygiene optimization
Sleep management strategies recognizing that sleep deprivation can exacerbate myoclonic seizures. Address sleep disorders that may worsen seizure control.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Progressive Myoclonic Epilepsy Type 7 C4015420?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Matsumoto N, Tanaka R, Yamamoto K. Progressive Myoclonic Epilepsies: Genetics and Clinical Spectrum. Epilepsy Res. 2022.
International League Against Epilepsy. Classification and Definition of Epilepsies with Myoclonic Seizures. Epilepsia. 2021.
Heberlein K, Klein KM, Neubauer BA. SCARB2 Mutations in Progressive Myoclonic Epilepsy Type 7. Neurology. 2020.
Orsini A, Valetto A, Minassiu C. Myoclonic Epilepsies in Children: A Comprehensive Review. J Child Neurol. 2023.
Medication Comparisons
Compare medications used to treat Progressive Myoclonic Epilepsy Type 7 C4015420. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy