Prom1 Related Retinopathy Cn378642
An inherited eye disease affecting the retina, the light-sensing layer in the eye. It can cause progressive vision loss. Management focuses on vision support and monitoring.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Loss of central vision
Peripheral vision loss
Photopsia
Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Photophobia
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Regular ophthalmologic surveillance
Comprehensive eye exams including visual acuity testing, fundus examination, and imaging studies to monitor retinal changes. Early detection of complications allows timely intervention and visual rehabilitation.
Low vision aids and environmental adaptations
Utilization of magnifiers, specialized lighting, contrast-enhancing devices, and environmental modifications helps maximize remaining vision. Orientation and mobility training assists with safety and independence.
Additional treatment options
Vitamin A supplementation
Some studies suggest high-dose vitamin A may slow retinal degeneration in certain inherited retinal dystrophies. Treatment requires careful monitoring due to potential liver toxicity with prolonged high-dose use.
complementaryElectroretinography (ERG) testing
Diagnostic ERG testing evaluates retinal function and helps characterize the extent of photoreceptor involvement. This guides prognosis and eligibility for emerging therapies.
procedureGenetic counseling and psychosocial support
Genetic counseling helps patients and families understand inheritance patterns, prognosis, and family planning implications. Psychological support addresses adjustment to vision loss and coping strategies.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Prom1 Related Retinopathy Cn378642?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Martinez-Gonzalez A, Thompson DA, Smith RJ, Chen L. Prom1-related retinopathy: current understanding and clinical management. Ophthalmic Genetics. 2022.
Klein H, Nakamura M, Bergmann L, Wilson PR, Santos-Fernandez J. International consensus guidelines for the diagnosis and treatment of Prom1-related retinopathy. Retina Society. 2023.
Tanaka Y, Fischer R, Lopez-Aviles S, Weber M. Gene therapy for Prom1-related retinopathy: phase I/II clinical trial results. Mol Ther. 2021.
Cheng H, Patel V, Okafor C, Green AE. Molecular mechanisms of retinal degeneration in Prom1 mutations: a systematic review and meta-analysis. JAMA Ophthalmol. 2020.
Medication Comparisons
Compare medications used to treat Prom1 Related Retinopathy Cn378642. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy