Pulmonary Embolism
Pulmonary embolism (PE) is a blockage of an artery in the lungs by a substance that has traveled from elsewhere in the body through the bloodstream.
Pulmonary embolism is a serious condition that occurs when a blood clot blocks one or more of the arteries in the lungs. Immediate medical attention is crucial.
Key facts at a glance
- ICD-10
- I26
- ICD-11
- BA00.0
- Body system
- cardiovascular
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Pleuritic chest pain
Syncope
Dyspnea
(cardiovascular)Chest discomfort or palpitations
(cardiovascular)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Hemoptysis
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Disease management and monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Anticoagulation Therapy
Anticoagulant medications are used to prevent further clot formation and allow the body's natural systems to dissolve existing clots. Treatment typically continues for several months depending on risk factors and recurrence likelihood.
Early Ambulation and Mobility
Progressive return to physical activity following stabilization reduces recurrence risk and improves overall recovery. Structured walking programs help prevent stasis in lower extremities.
Additional treatment options
Thrombolytic Therapy
Catheter-directed thrombolysis uses specialized medications to rapidly dissolve life-threatening clots in severe cases. This procedure requires intensive monitoring in a hospital setting due to bleeding risks.
procedureInferior Vena Cava Filter Placement
A mechanical device is placed in the main vein returning blood from the lower body to prevent clots from reaching the lungs. Used when anticoagulation is contraindicated or has failed.
procedureCompression Stocking Use
Graduated compression garments apply therapeutic pressure to improve venous return and reduce swelling in affected limbs. Consistent daily use supports long-term vein health.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Pulmonary Embolism?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism. Eur Heart J. 2020;41(4):543-603.
Bij P, van der Hulle T, Büller HR, Kamphuisen PW. Diagnosis and treatment of acute pulmonary embolism. Clin Chest Med. 2018;39(3):525-544.
Zhang S, Zhai Z, Yang Y, et al. Direct oral anticoagulants versus low-molecular-weight heparin for treatment of acute pulmonary embolism: a meta-analysis of randomized controlled trials. J Thromb Haemost. 2021;19(6):1493-1506.
Meyer G, Vicaut E, Danays T, et al. Fibrinolysis for patients with intermediate-risk pulmonary embolism. N Engl J Med. 2014;370(15):1402-1411.
Risk factors
Factors that raise the chance of developing this condition. Non-modifiable factors (such as genetics) cannot be changed; modifiable ones can be addressed.
When to seek medical help
Seek immediate medical attention if you experience symptoms such as sudden shortness of breath, chest pain, or coughing up blood.
Medication Comparisons
Compare medications used to treat Pulmonary Embolism. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsFrequently asked questions
What is the difference between a pulmonary embolism and a heart attack?
Can a pulmonary embolism cause death?
Is a pulmonary embolism the same as a blood clot in the lung?
Are there any home remedies for a pulmonary embolism?
What are the long-term effects of a pulmonary embolism?
Sources
- 1Mayo Clinic: https://www.mayoclinic.org/diseases-conditions/pulmonary-embolism/symptoms-causes/syc-20376262Source
- 2American Heart Association: https://www.heart.org/en/health-topics/pulmonary-embolismSource
- 3National Health Service (UK): https://www.nhs.uk/conditions/pulmonary-embolism/Source
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy