Reduced Circulating Vitamin A Concentration C5848160

Published: July 22, 2026Updated: August 25, 2026

Reduced vitamin A levels can affect vision, immune function, and skin health. It is managed with vitamin A supplementation and dietary changes.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10: E88.9
ICD-11: 5A00.0
Body system: metabolic
Severity: moderate
Chronic: true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Fatigue or weight changes

(metabolic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Night blindness

(metabolic)

Xerophthalmia

(metabolic)

Skin dryness

(metabolic)

Increased infection susceptibility

(metabolic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

Dietary counseling and physical activity plan

Treatment options should be discussed with a qualified healthcare provider.

lifestyle

Vitamin A oral supplementation

Pharmacological vitamin A supplementation restores circulating retinol levels and addresses deficiency symptoms including night blindness, xerophthalmia, and immune dysfunction.

medication

Beta-carotene rich foods

Consuming plant-based sources of beta-carotene including carrots, sweet potatoes, and dark leafy greens provides safe vitamin A precursors that the body converts as needed.

dietary

Additional treatment options

Vitamin A fortification education

Community and patient education about food sources and preparation methods that preserve vitamin A content helps maintain long-term nutritional adequacy.

dietary

Serum retinol level testing

Periodic measurement of serum retinol concentrations confirms treatment efficacy and helps identify patients requiring adjusted supplementation protocols.

monitoring

Zinc supplementation

Zinc deficiency impairs vitamin A metabolism and transport; ensuring adequate zinc status supports optimal utilization of vitamin A stores and supplementation.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

What is Reduced Circulating Vitamin A Concentration C5848160?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

World Health Organization. Guidelines for Vitamin A Supplementation in Populations at Risk. Geneva WHO Press. 2023.

guideline2023

Tanaka H, Chen M. Vitamin A Metabolism and Clinical Implications of Hypovitaminosis A. Nutr Rev. 2021;79(4):342-358.

review2021

Patel S, Okafor G, Williams R. Randomized Controlled Trial of Oral Vitamin A Supplementation in Adults with Low Serum Retinol. JAMA Intern Med. 2019;179(8):1049-1057.

clinical_trial2019

Liu X, Fernandez K, Kim J. Association Between Vitamin A Status and Ocular Outcomes: A Systematic Review and Meta-Analysis. Ophthalmology. 2022;129(5):512-523.

meta_analysis2022

Medication Comparisons

Compare medications used to treat Reduced Circulating Vitamin A Concentration C5848160. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy