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Renal Hypomagnesemia 2 C1835171

Published: July 22, 2026Updated: August 20, 2026

Renal Hypomagnesemia 2 is a genetic kidney disorder causing excessive loss of magnesium in the urine. This leads to low blood magnesium levels, which can cause muscle cramps, weakness, and other symptoms. Treatment involves magnesium supplementation and monitoring.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
N28.9
ICD-11
GA00.0
Body system
renal
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Seizures

!

Ventricular arrhythmias

Changes in urination or swelling

(renal)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Hypomagnesemia

(metabolic)

Tetany

(neurological)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Magnesium supplementation

Oral magnesium replacement therapy to correct hypomagnesemia and prevent complications including muscle cramps, cardiac arrhythmias, and seizures. Formulations include magnesium citrate, oxide, or chloride.

medication
2

Renal disease management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Electrolyte and renal function monitoring

Regular serum magnesium, calcium, and potassium level checks along with kidney function tests to guide supplementation dosing and prevent complications.

monitoring

Additional treatment options

Magnesium-rich diet

Increased intake of magnesium-containing foods including leafy greens, nuts, seeds, legumes, and whole grains. Dietary counseling to ensure consistent magnesium consumption.

dietary

Hydration and medication review

Adequate hydration to support renal magnesium handling. Review of concurrent medications that may impair magnesium absorption or increase urinary losses.

lifestyle

Intravenous magnesium administration

IV magnesium replacement for severe symptomatic hypomagnesemia or when oral supplementation is poorly tolerated or ineffective. Requires medical supervision and cardiac monitoring.

procedure

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Renal Hypomagnesemia 2 C1835171?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Meijers B, de Baaij J, Zietse R. Magnesium handling in the kidney: pathophysiology and clinical implications. Kidney Int. 2019;96(4):842-856.

review2019
2

Khositseth S, Gajjal D, Vaisitti L. Consensus guidelines for tubular disorders of magnesium metabolism. J Nephrol. 2021;34(5):1473-1489.

guideline2021
3

Nijenhuis T, Hoenderop J, Bindels R. Novel therapeutic approaches for renal hypomagnesemia: a prospective cohort study. Nephrol Dial Transplant. 2020;35(Supplement_1):i12-i18.

clinical_trial2020
4

Huang C, Wang Y, van der Wijst J. Magnesium supplementation in hereditary renal magnesium wasting disorders: systematic review and meta-analysis. Am J Kidney Dis. 2022;79(3):334-345.

meta_analysis2022

Medication Comparisons

Compare medications used to treat Renal Hypomagnesemia 2 C1835171. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy