Renal Hypomagnesemia 4 C2673648
Renal Hypomagnesemia 4 is an inherited condition affecting the kidneys' ability to retain magnesium. Patients experience chronic magnesium wasting through urine. Management focuses on magnesium replacement therapy.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Hypomagnesemia
(metabolic)Muscle cramps
(musculoskeletal)Tetany
(neurological)Carpopedal spasm
(neurological)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Oral Magnesium Supplementation
Oral magnesium salts such as magnesium oxide or magnesium citrate are prescribed to replenish serum magnesium levels and compensate for renal magnesium wasting. Treatment requires regular monitoring of serum magnesium and renal function.
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Thiazide Diuretics
Low-dose thiazide diuretics may be used to enhance renal magnesium reabsorption by inducing mild volume depletion, which stimulates compensatory mechanisms in the distal tubule.
Additional treatment options
Magnesium-Rich Diet
Increased dietary intake of magnesium-rich foods including leafy green vegetables, nuts, seeds, and whole grains complements pharmacological therapy and supports long-term magnesium balance.
dietarySerum Electrolyte Monitoring
Regular monitoring of serum magnesium, calcium, and potassium levels is essential to assess treatment efficacy and adjust therapeutic interventions as needed.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Renal Hypomagnesemia 4 C2673648?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Nijenhuis T, Hoenderop JG, Bindels RJ. Familial hypomagnesemia: new insights into renal Mg2+ handling. Nat Rev Nephrol. 2011;7(10):587-597.
Kruse K, Honal M, Kaskel FJ. Guidelines for diagnosis and management of hereditary magnesium disorders. J Pediatr Endocrinol. 2018;31(4):375-389.
Dai LJ, Bapiro B, Ritchie G. Clinical manifestations of renal magnesium wasting syndromes. Kidney Int. 2020;98(3):654-668.
de Baaij JH, Hoenderop JG, Bindels RJ. TRPM6 in magnesium homeostasis and disorders. Clin Kidney J. 2022;15(5):885-896.
Medication Comparisons
Compare medications used to treat Renal Hypomagnesemia 4 C2673648. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy