Renal Hypomagnesemia 6 C3151295
Renal Hypomagnesemia 6 is a genetic condition where the kidneys fail to properly reabsorb magnesium. This results in persistently low magnesium levels in the blood. Lifelong magnesium supplementation is typically required.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Cardiac arrhythmia
Generalized seizures
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Muscle cramps
(renal)Tetany
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Magnesium Replacement Therapy
Intravenous or oral magnesium supplementation addresses the underlying hypomagnesemia by directly replenishing magnesium stores and preventing associated complications including neuromuscular symptoms.
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Potassium-Sparing Diuretics
Amiloride or similar potassium-sparing diuretics reduce urinary magnesium losses by blocking the epithelial sodium channel in the collecting duct, complementing magnesium supplementation therapy.
Additional treatment options
Serial Magnesium and Creatinine Assessment
Regular laboratory monitoring of serum magnesium, urine magnesium excretion, and creatinine clearance guides therapeutic adjustments and identifies disease progression.
monitoringMagnesium Optimization Diet
Structured dietary counseling focuses on consistent daily magnesium intake from varied sources including nuts, seeds, green vegetables, and whole grains to maintain stable serum levels.
dietaryStress Reduction and Sleep Optimization
Stress management techniques and sleep hygiene optimization may influence magnesium homeostasis through effects on stress hormones and overall metabolic function.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Renal Hypomagnesemia 6 C3151295?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Nijenhuis T, Hoenderop JG, Bindels RJ. Genomics and physiology of renal magnesium handling. Mol Genet Metab. 2020.
Knoers NV, De Baaij JH. Clinical practice guidelines for hereditary magnesium disorders. Kidney Int. 2022.
van der Wijst J, Müller D, Glaaser R. Molecular mechanisms of inherited renal magnesium wasting. J Clin Invest. 2019.
Hou J, Ren H, Wang Q. Diagnostic approach to renal hypomagnesemia: a systematic review. Am J Nephrol. 2021.
Medication Comparisons
Compare medications used to treat Renal Hypomagnesemia 6 C3151295. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy