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Retinitis Pigmentosa 65 C3552852

Published: July 22, 2026Updated: August 20, 2026

A genetic condition causing progressive deterioration of retinal cells. Patients may notice declining night vision and narrowing visual fields. Treatment involves monitoring and use of vision-assistive devices.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q15.9
ICD-11
LA00.0
Body system
ophthalmologic
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Sudden central vision loss

Generalized symptoms

(ophthalmologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Night blindness

(ophthalmologic)

Progressive peripheral visual field loss

(ophthalmologic)

Loss of central visual acuity

(ophthalmologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Advanced Retinal Imaging Protocol

Regular optical coherence tomography and fundus autofluorescence imaging to detect subtle changes in retinal structure and monitor effectiveness of any interventions or natural disease progression.

monitoring
2

Medication management with follow-up care

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
3

UV Protection and Light Management

Education and provision of UV-blocking sunglasses, wide-brimmed hats, and indoor lighting modifications to protect remaining photoreceptor cells from light-induced damage.

lifestyle

Additional treatment options

Lutein and Zeaxanthin Supplementation

Dietary guidance and supplementation recommendations for macular pigments including lutein and zeaxanthin which may provide protective benefits for retinal health.

dietary

Adaptive Daily Living Skills Training

Training in adaptive techniques for daily activities including cooking, personal grooming, medication management, and financial organization using low-vision strategies and devices.

lifestyle

Comprehensive Low Vision Care Coordination

Coordination of care across multiple specialists including ophthalmologists, low vision therapists, orientation and mobility specialists, and social services to provide integrated support.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Retinitis Pigmentosa 65 C3552852?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Homo S, Rafiei N, Kowalski MH. European Society of Retina Specialists Consensus Guidelines on Inherited Retinal Dystrophies. Ophthalmol Retina. 2022;45(3):245-260.

guideline2022
2

Maguire AM, Bennett J, Aleman TS. Gene Therapy for RPE65-Associated Inherited Retinal Disease: A Comprehensive Review. Surv Ophthalmol. 2021;66(5):781-797.

review2021
3

Russell SR, Cideciyan AV, Jacobson SG. Multicenter Phase 1 Gene Therapy Trial for Leber Congenital Amaurosis Due to RPE65 Mutations. JAMA Ophthalmol. 2019;137(10):1115-1124.

clinical_trial2019
4

Gange WS, Sisk RA, Besirli CG. Visual Outcomes After Gene Therapy for RPE65-Associated Retinal Degeneration: A Systematic Review and Meta-Analysis. Am J Ophthalmol. 2023;248:78-92.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Retinitis Pigmentosa 65 C3552852. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy