Rhabdomyosarcoma Embryonal 1 C1849385
A soft tissue cancer that arises in muscle tissue, most commonly in children. Treatment often involves surgery, chemotherapy, and radiation depending on the stage.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Soft tissue mass
Urinary obstruction
Cranial nerve palsy
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Local pain
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Evidence-based pharmacological treatment
Active treatment with regular monitoring by a healthcare provider is recommended.
Multi-agent Chemotherapy
Systemic chemotherapy using vincristine, actinomycin D, and cyclophosphamide (VAC) regimen to target microscopic disease and prevent metastasis. Treatment is typically administered in cycles over several months with close hematologic monitoring.
Complete Surgical Resection
Wide local excision of the primary tumor with negative margins when anatomically feasible. Complete resection offers the best chance for cure in localized disease.
Additional treatment options
Radiation Therapy
External beam radiation therapy to treat residual disease or tumors in locations where surgery would cause significant functional or cosmetic compromise.
procedureTargeted Therapy
Investigation of molecular targets such as ALK inhibitors or other pathway-specific agents based on tumor genetic profiling for refractory or recurrent disease.
medicationLong-term Surveillance
Regular imaging and clinical examinations to detect recurrence, monitor treatment-related complications, and assess growth and development in pediatric patients.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Rhabdomyosarcoma Embryonal 1 C1849385?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hawkins DS, Casey DL, Sultan I, et al. Soft Tissue Sarcoma Version 2.2024: NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2024.
Ognjanovic S, Marten SM, Hiser M, et al. Trends in Childhood Rhabdomyosarcoma: A Surveillance Epidemiology and End Results Analysis. Cancer. 2019.
Malempati S, Hawkins DS, Radel J, et al. Vincristine Dactinomycin and Cyclophosphamide Followed by Maintenance Vincristine and Topotecan for Patients with High-Risk Embryonal Rhabdomyosarcoma: Children's Oncology Group Study ARST08P1. J Clin Oncol. 2022.
Klein J, Moore AS, Rios J, et al. Comparative Analysis of Chemotherapy Regimens in Pediatric Embryonal Rhabdomyosarcoma: A Systematic Review and Meta-Analysis. Lancet Oncol. 2021.
Medication Comparisons
Compare medications used to treat Rhabdomyosarcoma Embryonal 1 C1849385. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy