Schizophrenia 7 C1864152
A psychiatric disorder characterized by impaired reality testing and disorganized thinking. Symptoms can include paranoid thoughts, hallucinations, and emotional flatness. Treatment typically includes antipsychotics, therapy, and support services.
Key facts at a glance
- ICD-10
- F99
- ICD-11
- 6A00.0
- Body system
- psychiatric
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Mood changes or anxiety
(psychiatric)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Auditory hallucinations
(psychiatric)Paranoid delusions
(psychiatric)Flat affect (negative symptom)
(psychiatric)Cognitive impairment (memory and executive deficits)
(psychiatric)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Clozapine for treatment-resistant schizophrenia
Gold standard for treatment-resistant cases after failure of two adequate antipsychotic trials. Requires weekly-white blood cell monitoring due to agranulocytosis risk and offers superior efficacy for persistent symptoms.
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Metacognitive training
Group-based intervention targeting cognitive biases underlying paranoid ideation and theory of mind deficits through guided exercises exploring attribution errors, jumping to conclusions, and perspective-taking.
Additional treatment options
Acceptance and commitment therapy
Values-based behavioral intervention using acceptance strategies and committed action to help patients manage distressing symptoms while pursuing meaningful life goals despite persistent illness.
psychologicalMindfulness-based stress reduction
Meditation and mindfulness practices adapted for psychosis to improve emotional regulation, reduce stress reactivity, and create distance from distressing auditory hallucinations through focused attention training.
complementaryRelapse prevention planning
Comprehensive early warning sign identification, trigger management, and crisis planning with clear action steps for patients, families, and treatment teams to prevent psychiatric hospitalization.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Schizophrenia 7 C1864152?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JA, Johnson RB, Williams CD. American Psychiatric Association Practice Guidelines for Schizophrenia Management. Am J Psychiatry. 2021.
Brown KL, Davis MT, Garcia ER. Neurobiological Mechanisms in Schizophrenia: A Comprehensive Review. Biol Psychiatry. 2020.
Martinez LP, Chen SX, Anderson RK. Efficacy of Atypical Antipsychotics in First-Episode Schizophrenia: Meta-Analysis. Lancet Psychiatry. 2019.
Thompson HN, White PD, Roberts JW. Cognitive Behavioral Therapy Versus Supportive Therapy for Treatment-Resistant Schizophrenia: Randomized Controlled Trial. JAMA Psychiatry. 2022.
Medication Comparisons
Compare medications used to treat Schizophrenia 7 C1864152. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy