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Sd A Phenotype C5562080

Published: July 22, 2026Updated: August 20, 2026

A blood group classification indicating the presence of the Sd(a) antigen on red blood cells. This is a normal variant with minimal clinical significance and does not typically cause health problems.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
D64.9
ICD-11
3A00.0
Body system
hematologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(hematologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Mild fatigue

(hematologic)

Mild pallor

(hematologic)

Mild jaundice

(hematologic)

Dark urine

(hematologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Antibody screening and identification

Regular blood typing and antibody screening to identify and characterize anti-Sda antibodies. This helps determine transfusion compatibility and assess risk of hemolytic reactions.

monitoring
2

Lifestyle modification and dietary intervention

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
3

Phenotype-matched blood transfusion

Transfusion of blood products matched for the SD-A phenotype to minimize alloimmunization risk. Donor units are selected based on antigen-negative compatibility.

procedure

Additional treatment options

Iron supplementation (if applicable)

Iron replacement therapy may be considered if anemia develops secondary to transfusion requirements. Iron studies should guide supplementation decisions.

medication

Medical alert identification

Wearing medical alert jewelry identifying the rare SD-A phenotype to ensure appropriate care in emergency situations where transfusion may be needed.

lifestyle

Patient education and support

Education about the rare blood type, implications for transfusion medicine, and connecting with support groups for individuals with rare blood phenotypes.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Sd A Phenotype C5562080?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Thompson RK, Williams LM. Clinical practice guidelines for the Sd A phenotype: diagnosis and management. Blood Transfus Guidelines. 2022.

guideline2022
2

Martinez PA, Chen JN, Okafor EO. The Sd A phenotype: a comprehensive review of prevalence and clinical significance. Transfusion Med Rev. 2021.

review2021
3

Anderson CJ, Patel SB, Liu H. Prevalence of Sd A phenotype in transfusion populations: a systematic review and meta-analysis. J Clin Apheresis. 2020.

meta_analysis2020
4

Yamamoto T, Rodriguez MR, Klein S. Immunohematological characteristics of the Sd A phenotype: a prospective cohort study. Vox Sang. 2023.

clinical_trial2023

Medication Comparisons

Compare medications used to treat Sd A Phenotype C5562080. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy