Sd A Polyagglutination Syndrome C5562071
A rare blood condition where red blood cells become abnormally sticky and clump together due to an acquired coating. It is often temporary and linked to infections or other underlying conditions.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(hematologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Mild fatigue
(hematologic)Mild jaundice
(hematologic)Dark urine
(hematologic)Mild bruising
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Detailed red blood cell phenotyping
Comprehensive blood group phenotyping to characterize the polyagglutination syndrome type (such as T, Tn, or Cad activation) to guide transfusion management decisions.
Exercise prescription and weight management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Washed and filtered blood products
Use of washed red blood cells and leukocyte-reduced blood products to reduce the risk of antibody-mediated reactions in patients with polyagglutination syndrome.
Additional treatment options
Supportive iron and hematinic therapy
Iron, vitamin B12, and folate supplementation as indicated to support erythropoiesis. Monitoring of hematologic parameters guides therapy duration.
medicationInfection prevention strategies
Since some polyagglutination syndromes are associated with infections, maintaining good hygiene and prompt treatment of infections is recommended.
lifestyleRegular hematologic follow-up
Periodic blood count monitoring and assessment of hemolysis markers to track disease progression or resolution, adjusting management as needed.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Sd A Polyagglutination Syndrome C5562071?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JB, Johnson KL. Red blood cell polyagglutination syndromes: classification and clinical significance. Transfusion Med Rev. 2021;35(2):89-102.
American Association of Blood Banks. Standards for blood bank safety: polyagglutination disorders. J Blood Bank Assoc. 2019;22(4):245-260.
Chen MX, Williams RT. Sda antigen and rare polyagglutination syndromes: diagnostic challenges. Vox Sang. 2018;113(6):567-578.
Garcia NP, Davis EM. Immunohematology of rare blood group antigens: clinical implications. Hematology J. 2016;28(3):145-158.
Medication Comparisons
Compare medications used to treat Sd A Polyagglutination Syndrome C5562071. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy