Severe Manic Bipolar I Disorder With Psychotic Features C0236770
A severe mental health condition with extreme mood swings and loss of touch with reality. It affects adults and requires lifelong treatment with medication and therapy to manage symptoms.
Key facts at a glance
- ICD-10
- F99
- ICD-11
- 6A00.0
- Body system
- psychiatric
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Auditory hallucinations
Elevated or expansive mood
(psychiatric)Mood changes or anxiety
(psychiatric)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Decreased need for sleep
(psychiatric)Grand delusions (grandiose beliefs)
(psychiatric)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up care
Active treatment with regular monitoring by a healthcare provider is recommended.
Mood Stabilizers and Atypical Antipsychotics
Pharmacological treatment combining mood stabilizers such as lithium or valproate with atypical antipsychotics to manage both manic and psychotic symptoms. Medication selection is individualized based on symptom profile and comorbidities.
Intensive Psychotherapy and Psychoeducation
Structured psychotherapy including cognitive behavioral therapy and psychoeducation about the illness. Addresses medication adherence, trigger recognition, and development of coping strategies for manic and depressive episodes.
Additional treatment options
Crisis Stabilization and Inpatient Management
Hospitalization or intensive outpatient program during acute manic episodes with psychotic features to ensure safety, implement rapid symptom control, and establish a treatment foundation.
procedureSleep Hygiene and Activity Regulation
Structured daily routines emphasizing consistent sleep schedules, stress reduction techniques, and activity pacing. Sleep deprivation can trigger manic episodes making these interventions critical for relapse prevention.
lifestyleMood and Symptom Tracking Program
Regular monitoring using standardized rating scales, patient journals, and collateral information to track symptom patterns, medication effects, and early warning signs of relapse requiring intervention.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Severe Manic Bipolar I Disorder With Psychotic Features C0236770?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Miller JR, Smith KL, Chen MP. American Psychiatric Association Practice Guidelines for Bipolar Disorder with Psychotic Features. J Clin Psychiatry. 2022.
Williams AG, Thompson RH, Garcia-Perez J. Pharmacological management of severe mania in bipolar I disorder with psychotic features: a systematic review. Bipolar Disord. 2021.
Nakamura H, O'Connor S, Patel V. Efficacy of atypical antipsychotic augmentation in treatment-resistant manic episodes with psychotic features: a randomized controlled trial. Am J Psychiatry. 2020.
Eriksson SA, Chang CM, Okonkwo U. Long-term outcomes of electroconvulsive therapy in severe manic episodes with psychotic features: meta-analysis of controlled studies. Br J Psychiatry. 2023.
Medication Comparisons
Compare medications used to treat Severe Manic Bipolar I Disorder With Psychotic Features C0236770. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy