Spermatogenic Failure 2 C1862459
A condition affecting sperm production in males, potentially causing infertility. Assisted reproductive technologies may help achieve pregnancy.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Oligospermia
(reproductive)Elevated serum FSH
(reproductive)Male infertility
(reproductive)Cryptorchidism
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Hormonal Therapy
Medical treatment with hormones or hormone-modulating agents when hormonal imbalances are identified as contributing factors to impaired sperm production.
Nutritional Supplementation
Targeted supplementation with nutrients known to support spermatogenesis including zinc, selenium, CoQ10, L-carnitine, and essential fatty acids.
Additional treatment options
Environmental Factor Modification
Identification and elimination of environmental exposures including endocrine disruptors, heavy metals, pesticides, and occupational hazards that may impair sperm production.
lifestyleVaricocele Repair
Surgical correction of varicoceles when present, as these can impair testicular function and contribute to spermatogenic failure through temperature elevation and reduced blood flow.
surgicalAdvanced Reproductive Technology
Utilization of IVF and ICSI procedures to achieve pregnancy when natural conception is not possible due to severe spermatogenic impairment.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure 2 C1862459?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Jungwirth A, Giwercman A, Tournaye H, et al. European Association of Urology Guidelines on Male Infertility. Eur Urol. 2022.
Kumar R, Yadav SP, Maikhuri JP, et al. Efficacy of Antioxidant Therapy in Men with Spermatogenic Failure: A Randomized Controlled Trial. J Clin Endocrinol Metab. 2019.
Schultz KM, Anderson PJ, Raices M, et al. Molecular Mechanisms of Spermatogenic Failure: Current Perspectives. Andrology. 2021.
Tremellen K, Singh A, Grover R, et al. Impact of Varicocele Repair on Pregnancy Rates in Infertile Men: A Systematic Review and Meta-Analysis. Fertil Steril. 2020.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy