Spermatogenic Failure 70 C5676962
A genetic cause of male infertility where sperm production is impaired. This condition results from specific gene mutations. Family planning options like IVF may be considered.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Male infertility
(reproductive)Semen analysis abnormalities
(reproductive)Reduced sperm concentration
(reproductive)Elevated follicle‑stimulating hormone (FSH) levels
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Clomiphene citrate therapy
Selective estrogen receptor modulator that increases gonadotropin-releasing hormone (GnRH), FSH, and luteinizing hormone (LH) secretion. This off-label use can improve testosterone levels and stimulate sperm production.
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Environmental toxin avoidance
Comprehensive program identifying and eliminating exposure to endocrine-disrupting chemicals, pesticides, heavy metals, and industrial solvents. These agents can impair Sertoli cell function and disrupt spermatogenesis.
Additional treatment options
Zinc and folate optimization
Dietary supplementation with zinc (essential for testosterone synthesis and sperm metabolism) and folate (supports DNA synthesis in developing sperm cells). These micronutrients are critical cofactors in spermatogenesis.
dietaryMicrosurgical testicular sperm extraction (microTESE)
Advanced surgical technique using an operating microscope to identify and retrieve viable sperm-producing tubules from the testicle. This maximizes sperm retrieval rates while minimizing tissue damage.
surgicalStress reduction and counseling
Psychological support addressing the emotional impact of infertility diagnosis and treatment. Cognitive behavioral therapy and stress management techniques may improve treatment adherence and outcomes.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure 70 C5676962?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy