Spermatogenic Failure 76 C5774236
A genetic disorder affecting the testes' ability to produce mature sperm, resulting in male infertility. Treatment options focus on assisted reproductive technologies such as IVF.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Inability to conceive
(reproductive)Decreased semen volume
(reproductive)Low sperm concentration
(reproductive)Sperm morphological abnormalities
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anabolic Steroid Discontinuation with Recovery Protocol
Gradual tapering of exogenous androgen use to allow recovery of hypothalamic-pituitary-testicular axis function. May include adjuvant therapies to support endogenous testosterone restoration.
Drug therapy with clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Additional treatment options
Pelvic Floor Rehabilitation
Targeted pelvic floor muscle training to improve blood flow to pelvic organs and support erectile function. Includes biofeedback-assisted exercises and neuromuscular electrical stimulation when indicated.
physical_therapyHerbal Supplement Therapy
Evidence-informed use of herbal preparations such as fenugreek, ashwagandha, or tribulus terrestris that may support testosterone levels and sperm production through various mechanisms.
complementaryIntrauterine Insemination
Laboratory processing of ejaculated sperm to concentrate motile cells, which are then directly placed into the uterine cavity bypassing cervical mucus barriers.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure 76 C5774236?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
ASRM Practice Committee. Best practices for genetic evaluation of male infertility. Fertil Steril. 2022.
Okabe M, Tanaka S, Fernandez J. Clinical outcomes of ICSI with testicular sperm in patients with monogenic spermatogenic failure. Hum Reprod. 2021.
Neto FT, Bach PV, Smith JP. Genetic basis of non-obstructive azoospermia: a comprehensive review. Transl Androl Urol. 2021.
Krausz C, Cioppi F, Riera-Escamilla A. Testing for monogenic causes of spermatogenic failure: an update. Andrology. 2023.
Medication Comparisons
Compare medications used to treat Spermatogenic Failure 76 C5774236. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy