Spermatogenic Failure 85 C5882685
A genetic cause of impaired sperm development in the testes, leading to male infertility. Treatment focuses on fertility interventions.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Infertility
(reproductive)Semen analysis abnormality
(reproductive)Testicular hypotrophy
(reproductive)Chromosomal abnormality
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy with clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Gonadotropin Therapy (hCG/rFSH)
Exogenous gonadotropin administration to stimulate spermatogenesis directly through testicular hormone receptor activation.
Weight Management and Exercise
Structured program addressing obesity and sedentary behavior which negatively impact hormonal balance and sperm production.
Additional treatment options
Aromatase Inhibitor Therapy
Pharmacological reduction of estrogen excess through aromatase inhibition to improve testosterone-to-estradiol ratio.
medicationTesticular Sperm Extraction (TESE)
Surgical retrieval of sperm directly from testicular tissue for use in assisted reproduction when ejaculated sperm are unavailable.
surgicalFertility Counseling and Support
Psychological support addressing emotional stress, relationship impact, and coping strategies related to infertility diagnosis.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure 85 C5882685?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Jungwirth A, Diemer T, Dohle GR, et al. European Association of Urology Guidelines on Male Infertility. Eur Urol. 2022.
Krausz C, Cioppi F, Riera-Escamilla A. Genetic Factors of Non-Obstructive Azoospermia: Consequences on Clinical Practice. Hum Reprod Update. 2021.
Neto FT, Bach PV, Najari BB, et al. Spermatogenesis Recovery in Patients with Non-Obstructive Azoospermia: A Prospective Study. Andrology. 2020.
Ramasamy R, Trivedi NN, Rezk A, et al. Predictive Factors for Successful Microdissection TESE in Non-Obstructive Azoospermia: Systematic Review and Meta-Analysis. J Urol. 2023.
Medication Comparisons
Compare medications used to treat Spermatogenic Failure 85 C5882685. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy