Spermatogenic Failure 88 C5882706
A genetic disorder impairing normal sperm development, resulting in male infertility. Reproductive assistance may be beneficial.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Infertility
(reproductive)Reduced semen volume
(reproductive)Decreased sperm count
(reproductive)Testicular atrophy
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Hormone Replacement Therapy
Administration of gonadotropins such as human chorionic gonadotropin (hCG) and follicle-stimulating hormone (FSH) to stimulate spermatogenesis. This approach targets hormonal deficiencies that may be contributing to impaired sperm production.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Environmental Toxin Avoidance
Systematic identification and elimination of exposure to endocrine-disrupting chemicals, excessive heat, and reproductive toxins. Includes avoiding hot tubs, tight clothing, and occupational hazards.
Additional treatment options
Microscopic Testicular Sperm Extraction (microTESE)
Surgical procedure using microsurgical techniques to identify and retrieve viable sperm directly from testicular tissue. Recommended when other treatments have failed and assisted reproduction is planned.
surgicalAntioxidant Supplementation
Dietary supplementation with antioxidants including vitamin E, vitamin C, selenium, and coenzyme Q10 to reduce oxidative stress in testicular tissue and improve sperm quality.
dietaryAcupuncture
Traditional Chinese medicine approach using needle stimulation of specific points to improve testicular blood flow and hormonal balance. May be used as adjunct therapy.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure 88 C5882706?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
World Health Organization. WHO Laboratory Manual for the Examination and Processing of Human Semen, 6th Edition. Hum Reprod Update. 2021.
Krausz C, Riera-Escamilla A, Moreno-Mendoza D. Genetic causes of spermatogenic failure: A systematic review. Andrology. 2022.
Tüttelmann F, Ruckert C, Röpke A. Clinical outcomes following intracytoplasmic sperm injection in men with genetic causes of male infertility. Fertil Steril. 2020.
Aston KI, Conrad DF. Genomic analysis of non-obstructive azoospermia: A meta-analysis of gene expression studies. Mol Hum Reprod. 2019.
Medication Comparisons
Compare medications used to treat Spermatogenic Failure 88 C5882706. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy