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Spermatogenic Failure 92 C5935625

Published: July 22, 2026Updated: August 27, 2026

A genetic condition preventing normal sperm development in the testes, causing male infertility. This severe form typically requires assisted reproductive techniques.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
Q55.9
ICD-11
LA00.0
Body system
reproductive
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(reproductive)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Male infertility

(reproductive)

Oligospermia

(reproductive)

Asthenozoospermia

(reproductive)

Scrotal discomfort

(reproductive)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Pharmacological management with first-line agents

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
2

Testicular Sperm Extraction

Microsurgical retrieval of sperm directly from testicular tissue for use in IVF/ICSI when sperm are not present in ejaculate.

surgical
3

Hormone Optimization

Customized hormonal regimen using FSH, LH, or clomiphene to stimulate endogenous sperm production and improve testicular function.

medication

Additional treatment options

Heat Exposure Reduction

Lifestyle modifications eliminating factors that elevate testicular temperature including hot tubs, saunas, tight clothing, and prolonged sitting.

lifestyle

Nutritional Optimization

Dietary modifications emphasizing zinc, folate, omega-3 fatty acids, and B vitamins essential for normal sperm development and maturation.

dietary

Psychological Counseling

Specialized counseling addressing emotional stress, relationship strain, and depression commonly associated with infertility diagnosis.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Spermatogenic Failure 92 C5935625?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

American Society for Reproductive Medicine. Best practices for the evaluation and treatment of male factor infertility: a committee opinion. Fertil Steril. 2021.

guideline2021View source →
2

Krausz C, Cioppi F, Riera-Escandell ME. Genetic factors of non-obstructive azoospermia: consequences for clinical management. Andrology. 2020.

review2020
3

Tanaka A, Suzuki K, Iwamoto H, et al. Testicular sperm extraction in patients with non-obstructive azoospermia: a systematic review and meta-analysis. Hum Reprod Update. 2022.

meta_analysis2022
4

Guler I, Erdem M, Mehmet N, et al. Microdissection testicular sperm extraction in men with non-obstructive azoospermia: outcomes and prognostic factors. J Urol. 2021.

clinical_trial2021

Medication Comparisons

Compare medications used to treat Spermatogenic Failure 92 C5935625. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy