Spermatogenic Failure 93 C5935626
A genetic cause of male infertility where sperm production fails or is severely impaired. Affected males may consider donor sperm or adoption.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Azoospermia
(reproductive)Semen volume reduction
(reproductive)Sperm motility impairment
(reproductive)Testicular atrophy
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Genetic Counseling
Comprehensive genetic evaluation and counseling to assess hereditary factors, guide treatment selection, and inform family planning decisions.
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
ICSI with Preimplantation Testing
Intracytoplasmic sperm injection combined with genetic testing of embryos to maximize chances of healthy pregnancy and reduce genetic risk.
Additional treatment options
Antioxidant Therapy
Targeted antioxidant supplementation including vitamins C, E, and selenium to minimize DNA damage in developing sperm.
dietaryToxin Avoidance
Elimination of environmental toxins including pesticides, heavy metals, and endocrine-disrupting chemicals that may contribute to sperm DNA damage.
lifestyleFertility Support Groups
Participation in peer support groups providing emotional validation and shared experiences for couples navigating genetic-related infertility.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure 93 C5935626?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Krausz C, Cioppi F. Genetic Factors of Non-Obstructive Azoospermia: Consequences for Clinical Management. Hum Reprod Update. 2020.
Jungwirth A, Diemer T, Kopa Z, et al. European Association of Urology Guidelines on Male Infertility. Eur Urol. 2022.
Okutman O, Rhouma S, Muller J, et al. Molecular Characterization of Genetic Causes of Spermatogenic Failure. Andrology. 2021.
Tuttelmann F, Ruckert N, Rosing MA. Association of Y-Chromosome Microdeletions with Spermatogenic Failure: Systematic Review. Fertil Steril. 2019.
Medication Comparisons
Compare medications used to treat Spermatogenic Failure 93 C5935626. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy