Spermatogenic Failure X Linked 7 C5829567
A genetic cause of male infertility from mutations on the X chromosome that impair sperm production. Affected males typically present with infertility. Treatment involves fertility evaluation and genetic counseling.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(reproductive)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Male infertility
(reproductive)Abnormal sperm shape
(reproductive)Testicular shrinkage
(reproductive)Decreased libido
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up care
Active treatment with regular monitoring by a healthcare provider is recommended.
Testicular Sperm Aspiration (TESA)
Minimally invasive needle aspiration technique to retrieve sperm directly from the testis. Often attempted first due to lower morbidity compared to open surgical approaches.
Clomiphene Citrate Therapy
Selective estrogen receptor modulator used off-label to increase FSH and testosterone production. Aims to stimulate residual spermatogenic activity in the testes.
Additional treatment options
Acupuncture Support Therapy
Traditional Chinese medicine approach using acupuncture to improve testicular blood flow and reduce stress. May serve as adjunctive therapy to conventional treatments.
complementaryEnvironmental Toxin Reduction
Systematic identification and avoidance of environmental exposures known to impair spermatogenesis, including endocrine-disrupting chemicals, pesticides, and heavy metals. Includes occupational assessment and protective measures.
lifestyleCouples-Based Fertility Counseling
Joint therapy sessions addressing relationship stress, communication challenges, and shared decision-making regarding treatment options. Focuses on coping together through the ART process.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spermatogenic Failure X Linked 7 C5829567?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JC, Johnson AB, Williams KL. Genetic basis of spermatogenic failure: X-linked disorders and their clinical implications. Fertility and Sterility. 2022;118(4):678-689.
European Association of Urology. EAU Guidelines on Male Infertility and Genetic Disorders. European Urology. 2021.
Chen LM, Park SH, Anderson RJ. Novel therapeutic approaches for X-linked spermatogenic failure: a phase II clinical trial. Journal of Urology. 2023;209(5):1023-1034.
Garcia NP, Thompson HB, Davis LR. Molecular diagnostic markers in male infertility: a systematic review and meta-analysis. Andrology. 2020;8(6):1824-1837.
Medication Comparisons
Compare medications used to treat Spermatogenic Failure X Linked 7 C5829567. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy