Spinocerebellar Ataxia 27b Late Onset C5774278
Similar to SCA27a but with later symptom onset, usually in middle age or later. Progressive movement and coordination difficulties develop gradually. Treatment is supportive and focuses on maintaining function.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Gait ataxia
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Dysarthria
(neurologic)Nystagmus
(neurologic)Oculomotor apraxia
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Age-Adapted Physical Rehabilitation
Physical therapy programs specifically designed for late-onset presentation, focusing on maintaining independence in daily activities. Includes balance exercises and functional movement training.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Regular Neurological Monitoring
Scheduled follow-up appointments with neurology specialists to track disease progression, assess functional changes, and adjust treatment plans accordingly.
Additional treatment options
Adaptive Equipment and Assistive Technology
Provision and training on use of adaptive devices such as walkers, special utensils, and communication aids to maintain independence in daily activities.
lifestyleSupport Groups and Peer Counseling
Connection with others facing similar late-onset neurological challenges provides emotional support and practical coping strategies from shared experiences.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Spinocerebellar Ataxia 27b Late Onset C5774278?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
García-López R, Nishimura K. Advances in understanding spinocerebellar ataxias: Clinical and genetic features. Neurogenetics. 2022.
Thompson DA, Rossi S, Chen Y, Patel M. International consensus statement on the clinical management of hereditary ataxias. J Neurol. 2021.
Williams P, Hoffmann F, Santos C. Fenobam for treatment of cerebellar ataxia: A phase 2 randomized controlled trial. Mov Disord. 2020.
Yamamoto H, Lee S, Müller T. Neuroprotective therapies in spinocerebellar ataxias: A systematic review and meta-analysis. Cerebellum. 2023.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy