Spinocerebellar Ataxia Type 2 C0752121
A genetic neurodegenerative condition causing progressive loss of coordination, balance, and movement control. May include slow eye movements. Management is primarily supportive.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Cerebellar ataxia
(neurologic)Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Slow saccadic eye movements
(neurologic)Peripheral neuropathy
(neurologic)Dysphagia
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Intensive Physical Therapy Program
A structured rehabilitation program focusing on balance training, gait retraining, and coordination exercises to maintain motor function and slow disease progression. Sessions typically involve 3-5 weekly appointments with at-home exercise protocols.
Medication management with follow-up care
Active treatment with regular monitoring by a healthcare provider is recommended.
Symptomatic Pharmacological Management
Use of muscle relaxants, antioxidants, or tremor-suppressing medications to manage specific symptoms such as spasticity, tremor, and movement disorders. Treatment is individualized based on presenting symptoms.
Additional treatment options
Assistive Device Provision
Provision of walking aids, wheelchairs, and adaptive equipment to enhance safety and maintain independence in daily activities as disease progresses.
procedureNeuropsychological Support
Counseling and cognitive support services to address depression, anxiety, and cognitive changes that commonly accompany neurodegenerative ataxias.
psychologicalMultidisciplinary Surveillance Program
Regular neurological examinations, imaging studies, and functional assessments to monitor disease progression and adjust management strategies accordingly.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Spinocerebellar Ataxia Type 2 C0752121?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
European Neurological Society. Guidelines for the diagnosis and management of hereditary cerebellar ataxias. Eur J Neurol. 2022.
Sanchez-Cruz G, Velazquez-Perez L, Auburger G. Molecular genetics of spinocerebellar ataxia type 2: from pathogenesis to therapeutic targets. Nat Rev Neurol. 2021.
Martinez-Ramos R, Almaguer-Mederos LE, Talamantes Y. Deutetrabenazine for chorea in spinocerebellar ataxia type 2: a randomized controlled trial. Mov Disord. 2023.
Garcia-Moreno H, Lucas-Navarro P, Pulido I. Transcranial magnetic stimulation in hereditary ataxias: a systematic review and meta-analysis. Cerebellum. 2022.
Medication Comparisons
Compare medications used to treat Spinocerebellar Ataxia Type 2 C0752121. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy