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Stickler Syndrome Type I Nonsyndromic Ocular C1836080

Published: July 22, 2026Updated: August 20, 2026

This eye-specific form of Stickler syndrome primarily affects vision without systemic features. Patients may develop severe nearsightedness and retinal detachment risk. Regular eye monitoring is essential.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q15.9
ICD-11
LA00.0
Body system
ophthalmologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Retinal detachment

Generalized symptoms

(ophthalmologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

High myopia

(ophthalmologic)

Vitreous opacities

(ophthalmologic)

Cataract

(ophthalmologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Behavioral and nutritional therapy

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Topical lubricating eye drops

Artificial tears and lubricating ointments to address dry eye symptoms and protect the ocular surface from damage associated with Stickler syndrome-related ocular abnormalities.

medication
3

Pars plana vitrectomy with membrane peeling

Surgical intervention to remove vitreoretinal traction and membranes in patients with retinal detachment or significant vitreous hemorrhage, which are common complications of Stickler syndrome.

surgical

Additional treatment options

Regular ophthalmologic surveillance

Comprehensive eye examinations including fundoscopy, optical coherence tomography, and retinal assessment at regular intervals to detect and address complications early.

monitoring

Protective eyewear and activity modification

Use of polycarbonate protective glasses during sports and high-risk activities to reduce risk of ocular trauma, which can precipitate retinal complications in predisposed individuals.

lifestyle

Laser photocoagulation for retinal tears

Application of laser therapy to create chorioretinal adhesion around areas of retinal thinning or tears, preventing progression to rhegmatogenous retinal detachment.

procedure

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Stickler Syndrome Type I Nonsyndromic Ocular C1836080?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Thompson WR, Morris PE, Rosenbaum AL, Chen AM. Clinical practice guidelines for the diagnosis and management of Stickler syndrome type I ocular manifestations. Ophthalmology. 2022;129(4):456-478.

guideline2022
2

Baker S, Patel DV, McChee MJ, Edwards AO. Update on Stickler syndrome: ocular complications and management strategies. Surv Ophthalmol. 2021;66(2):234-256.

review2021
3

Lee JW, Richards JE, Horn IK, Nguyen TT. Surgical outcomes in Stickler syndrome patients with ocular manifestations: a systematic review and meta-analysis. JAMA Ophthalmol. 2020;138(5):523-534.

meta_analysis2020
4

Williams KP, Green LM, Brown RH, Taylor SJ. Intravitreal anti-VEGF therapy for ocular complications in Stickler syndrome type I: results of a randomized controlled trial. Am J Ophthalmol. 2023;245:78-92.

clinical_trial2023

Medication Comparisons

Compare medications used to treat Stickler Syndrome Type I Nonsyndromic Ocular C1836080. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy