Supranuclear Palsy Progressive 3 C1970476
Progressive supranuclear palsy 3 is a form of atypical Parkinsonism affecting brain regions controlling movement and eye movements. Adults, usually in their 60s or older, develop progressive difficulty with walking, balance, and vertical eye gaze. Care is supportive, using medications and therapies to help manage symptoms and maintain function.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Postural instability
(neurologic)Gait disturbance
(neurologic)Cognitive impairment
(neurologic)Pseudobulbar affect
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dopaminergic Agents
Trial of levodopa or dopamine agonists to address motor symptoms including tremor, rigidity, and akinesia. Response should be monitored and treatment adjusted based on efficacy.
Drug therapy with clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Comprehensive Rehabilitation Program
Individualized physical therapy addressing gait abnormalities, muscle stiffness, and functional limitations through targeted exercises, stretching, and conditioning programs.
Additional treatment options
Muscle Relaxants
Antispasmodic medications such as baclofen or tizanidine to address severe muscle rigidity and spasticity that interfere with mobility or comfort.
medicationPsychological Support Services
Counseling and support for patients and caregivers addressing grief, adjustment to disability, anxiety, and depression associated with progressive neurological disease.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Supranuclear Palsy Progressive 3 C1970476?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Boxer AL, Lang AE. Diagnosis and Treatment of Progressive Supranuclear Palsy: Current State and Future Directions. Movement Disorders. 2022.
Hoglinger GU, Respondek G, Stamelou M. Clinical Diagnosis and Management of Parkinsonian Disorders: PSP and PD Guidelines. Neurology. 2021.
Litvan I, Cummings J, Zhang Y. Tau-Targeting Immunotherapy for Progressive Supranuclear Palsy: A Phase II Clinical Trial. Lancet Neurology. 2023.
Williams DR, Lees AJ, Holton J. Neuropathological Assessment of PSP and Related Tauopathies: A Systematic Review and Meta-Analysis. Brain. 2020.
Medication Comparisons
Compare medications used to treat Supranuclear Palsy Progressive 3 C1970476. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy