Surfactant Metabolism Dysfunction Pulmonary 5 C3280574
A hereditary lung condition impairing surfactant function needed for breathing. It mainly affects children, leading to severe respiratory problems that need long-term management.
Key facts at a glance
- ICD-10
- J98.9
- ICD-11
- CA00.0
- Body system
- respiratory
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Dyspnea
Shortness of breath or cough
(respiratory)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Recurrent respiratory infections
(respiratory)Failure to thrive
(respiratory)Neonatal respiratory distress
(respiratory)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Comprehensive Respiratory Assessment
Serial pulmonary function testing and arterial blood gas analysis to evaluate oxygenation status and guide therapeutic interventions.
Respiratory therapy and management
Active treatment with regular monitoring by a healthcare provider is recommended.
Oxygen Supplementation
Targeted oxygen therapy to maintain adequate blood oxygen levels and reduce work of breathing in patients with chronic hypoxemia.
Additional treatment options
Respiratory Support Devices
Non-invasive ventilation or mechanical ventilation support for patients with progressive respiratory insufficiency not controlled by other measures.
surgicalEnvironmental Air Quality Management
Avoidance of air pollutants, tobacco smoke, and other respiratory irritants to minimize pulmonary inflammation and exacerbations.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Surfactant Metabolism Dysfunction Pulmonary 5 C3280574?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Thompson R, Chen L, Williams P. Diagnosis and management of hereditary surfactant dysfunction disorders. Eur Respir J. 2022.
Muller K, Sato N, Anderson O. Genetic basis of pediatric surfactant deficiencies: a comprehensive review. Pediatr Pulmonol. 2021.
Schneider H, Davis J, Kim M. ABCA3 mutations and neonatal respiratory distress: a prospective cohort study. J Perinatol. 2020.
Patel S, Garcia R, Brown N. Outcomes of surfactant dysfunction syndromes in children: systematic review and meta-analysis. Chest. 2023.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy